Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 147087   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 4 (Homo sapiens (Human))	BDBM147087 (US8957074, 127) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CC4CCC(CC3=O)N4)nc2n1-c1ccc(cc1)C(C)(C)C#N Show InChI InChI=1S/C31H33N9O2/c1-31(2,18-32)20-5-9-23(10-6-20)40-25(29(42)38(3)4)13-19-15-34-30(37-28(19)40)36-26-12-11-24(16-33-26)39-17-22-8-7-21(35-22)14-27(39)41/h5-6,9-13,15-16,21-22,35H,7-8,14,17H2,1-4H3,(H,33,34,36,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.5	22
Novartis AG US Patent					Assay Description An assay for monitoring CDK4/cyclin D1-catalyzed phosphorylation of pRb at the Ser780 site was performed using TR-FRET in a 384-well format, and was ...				US Patent US8957074 (2015) BindingDB Entry DOI: 10.7270/Q2K0730S
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM147087 (US8957074, 127) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CC4CCC(CC3=O)N4)nc2n1-c1ccc(cc1)C(C)(C)C#N Show InChI InChI=1S/C31H33N9O2/c1-31(2,18-32)20-5-9-23(10-6-20)40-25(29(42)38(3)4)13-19-15-34-30(37-28(19)40)36-26-12-11-24(16-33-26)39-17-22-8-7-21(35-22)14-27(39)41/h5-6,9-13,15-16,21-22,35H,7-8,14,17H2,1-4H3,(H,33,34,36,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description A 384-well microtiter IMAP-FP (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The s...				US Patent US8957074 (2015) BindingDB Entry DOI: 10.7270/Q2K0730S
					More data for this Ligand-Target Pair