BindingDB PrimarySearch

Found 9 hits of ic50 for monomerid = 163433
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM163433 (BA-1049 \| US11198680, Compound BA 1049 (R) \| US968...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
TBA					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM163433 (BA-1049 \| US11198680, Compound BA 1049 (R) \| US968...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 15 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
TBA					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM163433 (BA-1049 \| US11198680, Compound BA 1049 (R) \| US968...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 15 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
TBA					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Rattus norvegicus (Rat))	BDBM163433 (BA-1049 \| US11198680, Compound BA 1049 (R) \| US968...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	940	n/a	n/a	n/a	n/a	n/a	23
BIOAXONE BIOSCIENCES, INC. US Patent					Assay Description The inhibitor potency of BA-1049 (racemic mixture) and Fasudil (Calbiochem) were compared by fluorescent polarization assays performed using a Biomek...				US Patent US9687483 (2017) BindingDB Entry DOI: 10.7270/Q2H993CZ
BIOAXONE BIOSCIENCES, INC. US Patent					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Rattus norvegicus (Rat))	BDBM163433 (BA-1049 \| US11198680, Compound BA 1049 (R) \| US968...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	23
BIOAXONE BIOSCIENCES, INC. US Patent					Assay Description The inhibitor potency of BA-1049 (racemic mixture) and Fasudil (Calbiochem) were compared by fluorescent polarization assays performed using a Biomek...				US Patent US9687483 (2017) BindingDB Entry DOI: 10.7270/Q2H993CZ
BIOAXONE BIOSCIENCES, INC. US Patent					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM163433 (BA-1049 \| US11198680, Compound BA 1049 (R) \| US968...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
TBA					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Rattus norvegicus (Rat))	BDBM163433 (BA-1049 \| US11198680, Compound BA 1049 (R) \| US968...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	23
BIOAXONE BIOSCIENCES, INC. US Patent					Assay Description The inhibitor potency of BA-1049 (racemic mixture) and Fasudil (Calbiochem) were compared by fluorescent polarization assays performed using a Biomek...				US Patent US9687483 (2017) BindingDB Entry DOI: 10.7270/Q2H993CZ
BIOAXONE BIOSCIENCES, INC. US Patent					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM163433 (BA-1049 \| US11198680, Compound BA 1049 (R) \| US968...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	2.96E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 70 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
TBA					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM163433 (BA-1049 \| US11198680, Compound BA 1049 (R) \| US968...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	2.96E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 70 uM. The hi...				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1P2H
TBA					More data for this Ligand-Target Pair