BindingDB PrimarySearch

Found 23 hits of ic50 for monomerid = 22319
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Solute carrier organic anion transporter family member 1B1 (Homo sapiens (Human))	BDBM22319 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid \| ...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	603	n/a	n/a	n/a	n/a	n/a	n/a
KU Leuven Curated by ChEMBL					Assay Description pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cells				Mol Pharmacol 83: 1257-67 (2013) Article DOI: 10.1124/mol.112.084152 BindingDB Entry DOI: 10.7270/Q2TB18BP
KU Leuven Curated by ChEMBL					More data for this Ligand-Target Pair
Solute carrier organic anion transporter family member 1B3 (Homo sapiens (Human))	BDBM22319 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid \| ...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
KU Leuven Curated by ChEMBL					Assay Description pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B3-transfected CHO cells				Mol Pharmacol 83: 1257-67 (2013) Article DOI: 10.1124/mol.112.084152 BindingDB Entry DOI: 10.7270/Q2TB18BP
KU Leuven Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM22319 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid \| ...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PPAR-alpha (unknown origin) by SPA assay				Citation and Details Article DOI: 10.1007/s00044-008-9102-7 BindingDB Entry DOI: 10.7270/Q2K35XJ5
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM22319 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid \| ...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]GW2331 from Homo sapiens (human) PPARalpha receptor by scintillation proximity assay				Citation and Details Article DOI: 10.1007/s00044-012-0285-6 BindingDB Entry DOI: 10.7270/Q2MG7SDK
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM22319 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid \| ...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]BRL49653 from Homo sapiens (human) PPARgamma receptor by scintillation proximity assay				Citation and Details Article DOI: 10.1007/s00044-012-0285-6 BindingDB Entry DOI: 10.7270/Q2MG7SDK
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Fatty acid-binding protein, adipocyte (Homo sapiens (Human))	BDBM22319 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid \| ...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2022.114604 BindingDB Entry DOI: 10.7270/Q2J38XJ0
TBA					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM22319 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid \| ...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]GW2433 from Homo sapiens (human) PPARdelta receptor by scintillation proximity assay				Citation and Details Article DOI: 10.1007/s00044-012-0285-6 BindingDB Entry DOI: 10.7270/Q2MG7SDK
TBA					More data for this Ligand-Target Pair
60 kDa heat shock protein, mitochondrial (Homo sapiens)	BDBM22319 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid \| ...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human N-terminal octa-His-tagged HSP60 expressed in Escherichia coli Rosetta(DE3) pLysS/human HSP10 expressed in Escherichia coli Roset...				Bioorg Med Chem Lett 29: 1106-1112 (2019) Article DOI: 10.1016/j.bmcl.2019.02.028 BindingDB Entry DOI: 10.7270/Q2NZ8C33
Indiana University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty acid-binding protein, adipocyte (Homo sapiens (Human))	BDBM22319 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid \| ...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars		n/a	n/a	5.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (RAT)	BDBM22319 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid \| ...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Inhibition of L-type calcium channel measured using whole-cell patch clamp in rat ventricular myocytes				J Appl Toxicol 32: 858-66 (2012) Article DOI: 10.1002/jat.2784 BindingDB Entry DOI: 10.7270/Q2D79D5C
Jagiellonian University Curated by ChEMBL					More data for this Ligand-Target Pair
Co-chaperonin GroES (Escherichia coli)	BDBM22319 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid \| ...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Inhibition of Escherichia coli GroEL expressed in Escherichia coliDH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed a...				Bioorg Med Chem Lett 29: 1106-1112 (2019) Article DOI: 10.1016/j.bmcl.2019.02.028 BindingDB Entry DOI: 10.7270/Q2NZ8C33
Indiana University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (RAT)	BDBM22319 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid \| ...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Inhibition of L-type calcium channel measured using whole-cell patch clamp in rat ventricular myocytes				J Appl Toxicol 32: 858-66 (2012) Article DOI: 10.1002/jat.2784 BindingDB Entry DOI: 10.7270/Q2D79D5C
Jagiellonian University Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 2 (Rattus norvegicus)	BDBM22319 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid \| ...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Research Council (CNR) Curated by ChEMBL					Assay Description Antagonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as inhibition of LPC-induced Ca2+ levels preincubated for 5 mins foll...				J Med Chem 61: 8255-8281 (2018) Article DOI: 10.1021/acs.jmedchem.8b00734 BindingDB Entry DOI: 10.7270/Q2222XFP
National Research Council (CNR) Curated by ChEMBL					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 2 (Rattus norvegicus)	BDBM22319 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid \| ...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Research Council (CNR) Curated by ChEMBL					Assay Description Antagonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as inhibition of CBD-induced Ca2+ levels preincubated for 5 mins foll...				J Med Chem 61: 8255-8281 (2018) Article DOI: 10.1021/acs.jmedchem.8b00734 BindingDB Entry DOI: 10.7270/Q2222XFP
National Research Council (CNR) Curated by ChEMBL					More data for this Ligand-Target Pair
Co-chaperonin GroES (Escherichia coli)	BDBM22319 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid \| ...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Inhibition of Escherichia coli GroEL expressed in Escherichia coli DH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed ...				Bioorg Med Chem Lett 29: 1106-1112 (2019) Article DOI: 10.1016/j.bmcl.2019.02.028 BindingDB Entry DOI: 10.7270/Q2NZ8C33
Indiana University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM22319 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid \| ...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.82E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of aromatase in human placental microsomes by radiometric method				J Nat Prod 69: 700-3 (2006) Article DOI: 10.1021/np050513p BindingDB Entry DOI: 10.7270/Q2J96647
University of Illinois at Chicago Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM22319 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid \| ...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of FAAH				J Med Chem 51: 7327-43 (2009) Article DOI: 10.1021/jm800311k BindingDB Entry DOI: 10.7270/Q2J67HT8
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 gamma (Homo sapiens (Human))	BDBM22319 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid \| ...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd. Curated by ChEMBL					Assay Description Concentration required to inhibit human Cytosolic phospholipase A2				Bioorg Med Chem Lett 11: 587-90 (2001) BindingDB Entry DOI: 10.7270/Q2ST7P4R
Shionogi & Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Thiosulfate sulfurtransferase (Homo sapiens)	BDBM22319 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid \| ...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Inhibition of native rhodanese (unknown origin) assessed as reduction in rhodanese enzyme activity after 45 mins by Fe(SCN)3 dye based spectrometric ...				Bioorg Med Chem Lett 29: 1106-1112 (2019) Article DOI: 10.1016/j.bmcl.2019.02.028 BindingDB Entry DOI: 10.7270/Q2NZ8C33
Indiana University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Tissue factor (Homo sapiens (Human))	BDBM22319 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid \| ...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.05E+5	n/a	n/a	n/a	n/a	n/a	n/a
Searle Discovery Research Curated by ChEMBL					Assay Description Inhibition of amidolytic activity of human tissue factor/human factor 7a				J Nat Prod 61: 1352-5 (1999) Article DOI: 10.1021/np980117p BindingDB Entry DOI: 10.7270/Q2SF2VXF
Searle Discovery Research Curated by ChEMBL					More data for this Ligand-Target Pair
Trypsin (Sus scrofa)	BDBM22319 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid \| ...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Searle Discovery Research Curated by ChEMBL					Assay Description Inhibition of pig pancreatic trypsin after 15 mins				J Nat Prod 61: 1352-5 (1999) Article DOI: 10.1021/np980117p BindingDB Entry DOI: 10.7270/Q2SF2VXF
Searle Discovery Research Curated by ChEMBL					More data for this Ligand-Target Pair
Lanosterol 14-alpha demethylase (Homo sapiens (Human))	BDBM22319 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid \| ...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
ACT LLC Curated by ChEMBL					Assay Description Inhibition of human CYP51 expressed in Topp 3 cells by lanosterol demethylase assay				Drug Metab Dispos 35: 493-500 (2007) Article DOI: 10.1124/dmd.106.013888 BindingDB Entry DOI: 10.7270/Q2DF6S2H
ACT LLC Curated by ChEMBL					More data for this Ligand-Target Pair
Chaperonin GroEL (Escherichia coli)	BDBM22319 ((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid \| ...) Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Inhibition of ATPase activity of Escherichia coli GroEL expressed in Escherichia coliDH5alpha incubated for 60 mins using ATP by spectrometric analys...				Bioorg Med Chem Lett 29: 1106-1112 (2019) Article DOI: 10.1016/j.bmcl.2019.02.028 BindingDB Entry DOI: 10.7270/Q2NZ8C33
Indiana University School of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair