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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 226866   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
High affinity nerve growth factor receptor [441-796]


(Homo sapiens (Human))
BDBM226866
PNG
(US9328096, 559)
Show SMILES Fc1cccnc1-c1cc(C(=O)Nc2cc(nn2-c2ccccc2)C(=O)NCc2ccncn2)c(Cl)cc1Cl
Show InChI InChI=1S/C27H18Cl2FN7O2/c28-20-12-21(29)19(11-18(20)25-22(30)7-4-9-32-25)26(38)35-24-13-23(36-37(24)17-5-2-1-3-6-17)27(39)33-14-16-8-10-31-15-34-16/h1-13,15H,14H2,(H,33,39)(H,35,38)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.68n/an/an/an/an/a37



Pfizer Inc.

US Patent


Assay Description
TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...


US Patent US9328096 (2016)


BindingDB Entry DOI: 10.7270/Q2FN152J
More data for this
Ligand-Target Pair