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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 243041   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Lyn


(Homo sapiens (Human))
BDBM243041
PNG
(A-419259)
Show SMILES CN1CCN(CC1)[C@H]1CCC(CC1)n1cc(-c2ccc(Oc3ccccc3)cc2)c2c(N)ncnc12 |r,wD:7.7,(26.44,-17.33,;25.67,-18.66,;25.16,-19.93,;25.3,-21.48,;23.96,-22.25,;24.33,-20.97,;24.33,-19.43,;22.48,-22.65,;22.48,-21.11,;21.14,-20.34,;19.81,-21.11,;19.81,-22.65,;21.14,-23.42,;18.32,-20.71,;19.23,-19.47,;18.32,-18.22,;18.8,-16.76,;20.3,-16.44,;20.78,-14.97,;19.75,-13.83,;20.22,-12.36,;21.73,-12.04,;22.76,-13.19,;24.27,-12.87,;24.74,-11.4,;23.71,-10.26,;22.21,-10.58,;18.24,-14.15,;17.77,-15.61,;16.86,-18.7,;15.52,-17.93,;15.52,-16.39,;14.19,-18.7,;14.19,-20.24,;15.52,-21.01,;16.86,-20.24,)|
Show InChI InChI=1/C29H34N6O/c1-33-15-17-34(18-16-33)22-9-11-23(12-10-22)35-19-26(27-28(30)31-20-32-29(27)35)21-7-13-25(14-8-21)36-24-5-3-2-4-6-24/h2-8,13-14,19-20,22-23H,9-12,15-18H2,1H3,(H2,30,31,32)/t22-,23?
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.300n/an/an/an/an/a22



Ankara University



Assay Description
Kinase activity (Src-family kinases, Hck, Lyn, Fyn, and c-Src) and the effect of the molecules were determined by ProFluor Src-Family Kinase Assay Ki...


J Enzyme Inhib Med Chem 28: 1080-7 (2013)


Article DOI: 10.3109/14756366.2012.715288
BindingDB Entry DOI: 10.7270/Q2KD1WTX
More data for this
Ligand-Target Pair