Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bromodomain-containing protein 4 [75-147] (Homo sapiens (Human)) | BDBM249311 (US10017501, Compound 1020-239 | US9458145, 1020-23...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.90 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Gilead Sciences, Inc. US Patent | Assay Description The labeled ligand specifically binds BRD4-1 and BRD4-2 and can be displaced by a small molecule inhibitor that shares a similar or overlapping bindi... | US Patent US9458145 (2016) BindingDB Entry DOI: 10.7270/Q26Q1W53 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 [368-440] (Homo sapiens (Human)) | BDBM249311 (US10017501, Compound 1020-239 | US9458145, 1020-23...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Gilead Sciences, Inc. US Patent | Assay Description The labeled ligand specifically binds BRD4-1 and BRD4-2 and can be displaced by a small molecule inhibitor that shares a similar or overlapping bindi... | US Patent US9458145 (2016) BindingDB Entry DOI: 10.7270/Q26Q1W53 | |||||||||||
More data for this Ligand-Target Pair |