Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 25489   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM25489 (Dihydropyrimidine, 18 | N-(1H-indazol-5-yl)-2-(4-m...) Show SMILES COc1ccc(cc1)C1=NC(C)=C(C(C)N1)C(=O)Nc1ccc2[nH]ncc2c1 |c:12,t:9| Show InChI InChI=1S/C21H21N5O2/c1-12-19(21(27)25-16-6-9-18-15(10-16)11-22-26-18)13(2)24-20(23-12)14-4-7-17(28-3)8-5-14/h4-12H,1-3H3,(H,22,26)(H,23,24)(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	863	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...				J Med Chem 51: 6631-4 (2008) Article DOI: 10.1021/jm8005096 BindingDB Entry DOI: 10.7270/Q2F47MFZ
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