Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Integrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1 (Mus musculus (Mouse)-Homo sapiens (Human)) | BDBM260659 (US9533985, 47) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.320 | n/a | n/a | n/a | n/a | 9.6 | 4 |
EA Pharma Co., Ltd. US Patent | Assay Description The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA... | US Patent US9533985 (2017) BindingDB Entry DOI: 10.7270/Q20C4TQ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-4/Integrin beta-7/Mucosal addressin cell adhesion molecule 1 (Mus musculus (Mouse)-Homo sapiens (Human)) | BDBM260659 (US9533985, 47) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 20 | n/a | n/a | n/a | n/a | 9.6 | 4 |
EA Pharma Co., Ltd. US Patent | Assay Description The ability of test substances to inhibit the binding of a human B cell line, RPMI-8866, which is known to express α4β7 integrin, to MAdCA... | US Patent US9533985 (2017) BindingDB Entry DOI: 10.7270/Q20C4TQ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-4/Integrin beta-1/Vascular cell adhesion protein 1 (Homo sapiens (Human)) | BDBM260659 (US9533985, 47) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 340 | n/a | n/a | n/a | n/a | 9.6 | 4 |
EA Pharma Co., Ltd. US Patent | Assay Description The ability of test substances to inhibit the binding of a human T-cell line, Jurkat, which is known to express α4β1 integrin, to VCAM-1 w... | US Patent US9533985 (2017) BindingDB Entry DOI: 10.7270/Q20C4TQ8 | |||||||||||
More data for this Ligand-Target Pair |