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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 325133   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ubiquitin carboxyl-terminal hydrolase 1


(Homo sapiens (Human))
BDBM325133
PNG
(9-(4-(4-((dimethylamino)methyl)-1H-1,2,3-triazol-1...)
Show SMILES CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)-n3cc(CN(C)C)nn3)c2n1
Show InChI InChI=1S/C26H28N8O/c1-17(2)21-7-5-6-8-22(21)24-27-13-23-25(29-24)33(26(35)28-23)14-18-9-11-20(12-10-18)34-16-19(30-31-34)15-32(3)4/h5-13,16-17H,14-15H2,1-4H3,(H,28,35)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<0.00200n/an/an/an/an/an/a



FORMA Therapeutics, Inc.

US Patent


Assay Description
The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...


US Patent US10189841 (2019)


BindingDB Entry DOI: 10.7270/Q22R3TRR
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1


(Homo sapiens (Human))
BDBM325133
PNG
(9-(4-(4-((dimethylamino)methyl)-1H-1,2,3-triazol-1...)
Show SMILES CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)-n3cc(CN(C)C)nn3)c2n1
Show InChI InChI=1S/C26H28N8O/c1-17(2)21-7-5-6-8-22(21)24-27-13-23-25(29-24)33(26(35)28-23)14-18-9-11-20(12-10-18)34-16-19(30-31-34)15-32(3)4/h5-13,16-17H,14-15H2,1-4H3,(H,28,35)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>2.00E+3n/an/an/an/an/an/a



FORMA Therapeutics, Inc.

US Patent


Assay Description
The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...


US Patent US10399980 (2019)


BindingDB Entry DOI: 10.7270/Q23J3GCX
More data for this
Ligand-Target Pair