BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 341126   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM341126
PNG
(1-{4-Hydroxy-5-methoxy-2-[(3S)-3-[(4-methylpiperaz...)
Show SMILES COc1cc(c(cc1O)C(=O)N1Cc2ccccc2C[C@H]1CN1CCN(C)CC1)-n1cc(C(=O)N(c2ccccc2)c2ccc3[nH]ccc3c2)c2ccccc12
Show InChI InChI=1S/C46H44N6O4/c1-48-20-22-49(23-21-48)29-36-24-31-10-6-7-11-33(31)28-50(36)45(54)38-26-43(53)44(56-2)27-42(38)51-30-39(37-14-8-9-15-41(37)51)46(55)52(34-12-4-3-5-13-34)35-16-17-40-32(25-35)18-19-47-40/h3-19,25-27,30,36,47,53H,20-24,28-29H2,1-2H3/t36-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.40n/an/an/an/an/an/a



LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent


Assay Description
Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...

US Patent US9765056 (2017)


BindingDB Entry DOI: 10.7270/Q2T72KJF
More data for this
Ligand-Target Pair