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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 341456   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tryptophan 5-hydroxylase 1


(Homo sapiens (Human))		BDBM341456
PNG
(6-chloro-5-(2-(5-(3-fluorothiophen-2-yl)-2-methyl-...)
Show SMILES CN(C)C(=O)c1ccc(OCC(=O)N2CCc3nc4sc(C)nn4c3C2c2sccc2F)c(Cl)n1
Show InChI InChI=1S/C22H20ClFN6O3S2/c1-11-27-30-17-13(26-22(30)35-11)6-8-29(18(17)19-12(24)7-9-34-19)16(31)10-33-15-5-4-14(25-20(15)23)21(32)28(2)3/h4-5,7,9,18H,6,8,10H2,1-3H3
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US Patent
n/an/a 5n/an/an/an/an/an/a



ACTELION PHARMACEUTICALS LTD

US Patent


Assay Description
To generate the enzyme, full length human TPH1 is cloned into the plasmid pET20b(+) (Novagen) and expressed in E. coli. The bacterial cells are ruptu...

US Patent US9765092 (2017)


BindingDB Entry DOI: 10.7270/Q21N838B
More data for this
Ligand-Target Pair