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Compile Data Set for Download or QSAR

Found 3 hits of ic50 for monomerid = 350249   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cyclin-C/Cyclin-dependent kinase 8


(Homo sapiens (Human))
BDBM350249
PNG
(US10208056, Compound 76)
Show SMILES NC(=O)c1cc2c(-c3ccncc3OC22CCC2)n1CCF
Show InChI InChI=1S/C16H16FN3O2/c17-5-7-20-12(15(18)21)8-11-14(20)10-2-6-19-9-13(10)22-16(11)3-1-4-16/h2,6,8-9H,1,3-5,7H2,(H2,18,21)
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.262n/an/an/an/an/an/a



FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO)

US Patent


Assay Description
The binding assay relies on the LanthaScreen™ Eu-Kinase Binding Assay (Invitrogen. This is a kinase assay platform based on measuring the binding and...


US Patent US10208056 (2019)


BindingDB Entry DOI: 10.7270/Q2GB266B
More data for this
Ligand-Target Pair
Cyclin-C/Cyclin-dependent kinase 19


(Homo sapiens (Human))
BDBM350249
PNG
(US10208056, Compound 76)
Show SMILES NC(=O)c1cc2c(-c3ccncc3OC22CCC2)n1CCF
Show InChI InChI=1S/C16H16FN3O2/c17-5-7-20-12(15(18)21)8-11-14(20)10-2-6-19-9-13(10)22-16(11)3-1-4-16/h2,6,8-9H,1,3-5,7H2,(H2,18,21)
PDB

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.827n/an/an/an/an/an/a



FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO)

US Patent


Assay Description
The binding assay relies on the LanthaScreen™ Eu-Kinase Binding Assay (Invitrogen). This is a kinase assay platform based on measuring the binding an...


US Patent US10208056 (2019)


BindingDB Entry DOI: 10.7270/Q2GB266B
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase haspin


(Homo sapiens (Human))
BDBM350249
PNG
(US10208056, Compound 76)
Show SMILES NC(=O)c1cc2c(-c3ccncc3OC22CCC2)n1CCF
Show InChI InChI=1S/C16H16FN3O2/c17-5-7-20-12(15(18)21)8-11-14(20)10-2-6-19-9-13(10)22-16(11)3-1-4-16/h2,6,8-9H,1,3-5,7H2,(H2,18,21)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 24.2n/an/an/an/an/an/a



FUNDACIÓN DEL SECTOR PÚBLICO ESTATAL CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS CARLOS III (F.S.P. CNIO)

US Patent


Assay Description
The kinase assay relies on ADP-GloKM biochemical kinase assay (Promega). This is a luminescent kinase assay that measures ADP formed from a kinase re...


US Patent US10208056 (2019)


BindingDB Entry DOI: 10.7270/Q2GB266B
More data for this
Ligand-Target Pair