Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin G/H synthase 2 (Ovis aries (Sheep)) | BDBM38550 (3-METHYL-1-PHENYL-2-PYRAZOLIN-5-ONE | 5-methyl-2-p...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.50E+4 | n/a | n/a | n/a | n/a | n/a | 37 |
Y. B. Chavan College of Pharmacy | Assay Description The COX-1/COX-2 inhibition assay was done using an enzyme immunoassay (EIA) kit. The reaction buffer (960 uL), containing 0.1 M Tris-HCl (pH 8.0), 5... | Chem Biol Drug Des 84: 409-19 (2014) Article DOI: 10.1111/cbdd.12324 BindingDB Entry DOI: 10.7270/Q24M937V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM38550 (3-METHYL-1-PHENYL-2-PYRAZOLIN-5-ONE | 5-methyl-2-p...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | >5.96E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ... | PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2F769ZM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM38550 (3-METHYL-1-PHENYL-2-PYRAZOLIN-5-ONE | 5-methyl-2-p...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | 37 |
Y. B. Chavan College of Pharmacy | Assay Description The COX-1/COX-2 inhibition assay was done using an enzyme immunoassay (EIA) kit. The reaction buffer (960 uL), containing 0.1 M Tris-HCl (pH 8.0), 5... | Chem Biol Drug Des 84: 409-19 (2014) Article DOI: 10.1111/cbdd.12324 BindingDB Entry DOI: 10.7270/Q24M937V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mevalonate kinase (Streptococcus pneumoniae D39) | BDBM38550 (3-METHYL-1-PHENYL-2-PYRAZOLIN-5-ONE | 5-methyl-2-p...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | >1.00E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
SRMLSC Curated by PubChem BioAssay | Assay Description Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C... | PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q23X852V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mevalonate kinase (Streptococcus pneumoniae D39) | BDBM38550 (3-METHYL-1-PHENYL-2-PYRAZOLIN-5-ONE | 5-methyl-2-p...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | >1.00E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
SRMLSC Curated by PubChem BioAssay | Assay Description Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C... | PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q27P8WSS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mevalonate kinase (Streptococcus pneumoniae D39) | BDBM38550 (3-METHYL-1-PHENYL-2-PYRAZOLIN-5-ONE | 5-methyl-2-p...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | >1.00E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
SRMLSC Curated by PubChem BioAssay | Assay Description Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C... | PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2CF9NG2 | |||||||||||
More data for this Ligand-Target Pair |