BindingDB PrimarySearch

Found 7 hits of ic50 for monomerid = 50005886
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Neutrophil elastase (Homo sapiens (Human))	BDBM50005886 (1,8-Dihydroxy-3-methoxy-6-methylanthraquinone \| 1,...) Show SMILES COc1cc(O)c2C(=O)c3c(O)cc(C)cc3C(=O)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
School of Chemistry and Biochemistry Curated by ChEMBL					Assay Description Compound was tested for the enzyme inhibitory activity against Human Leukocyte Elastase (HLE) at 65 uM concentration				J Med Chem 35: 1597-605 (1992) BindingDB Entry DOI: 10.7270/Q2QN67D7
School of Chemistry and Biochemistry Curated by ChEMBL					More data for this Ligand-Target Pair
Tissue alpha-L-fucosidase (Bos taurus)	BDBM50005886 (1,8-Dihydroxy-3-methoxy-6-methylanthraquinone \| 1,...) Show SMILES COc1cc(O)c2C(=O)c3c(O)cc(C)cc3C(=O)c2c1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of bovine kidney alpha-fucosidase using PNPG as substrate incubated for 10 mins by spectrophotometric method				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112034 BindingDB Entry DOI: 10.7270/Q2KW5KN9
TBA					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM50005886 (1,8-Dihydroxy-3-methoxy-6-methylanthraquinone \| 1,...) Show SMILES COc1cc(O)c2C(=O)c3c(O)cc(C)cc3C(=O)c2c1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of acid-mediated aggregation of TTR V30M mutant (unknown origin) expressed in Escherichia coli pretreated for 30 mins at pH 7 followed by ...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116292 BindingDB Entry DOI: 10.7270/Q2222ZH0
TBA					More data for this Ligand-Target Pair
Thioredoxin reductase 2, mitochondrial (Rattus norvegicus)	BDBM50005886 (1,8-Dihydroxy-3-methoxy-6-methylanthraquinone \| 1,...) Show SMILES COc1cc(O)c2C(=O)c3c(O)cc(C)cc3C(=O)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.32E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Padova Curated by ChEMBL					Assay Description Inhibition of rat liver mitochondrial TrxR2 by spectrophotometry				Bioorg Med Chem 19: 631-41 (2011) Article DOI: 10.1016/j.bmc.2010.10.045 BindingDB Entry DOI: 10.7270/Q25D8S4N
University of Padova Curated by ChEMBL					More data for this Ligand-Target Pair
Genome polyprotein (Human rhinovirus B)	BDBM50005886 (1,8-Dihydroxy-3-methoxy-6-methylanthraquinone \| 1,...) Show SMILES COc1cc(O)c2C(=O)c3c(O)cc(C)cc3C(=O)c2c1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HRV 3Cpro using HPLC assay				Bioorg Med Chem Lett 11: 3143-6 (2001) BindingDB Entry DOI: 10.7270/Q2T43SDG
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Thioredoxin reductase 1, cytoplasmic (Rattus norvegicus)	BDBM50005886 (1,8-Dihydroxy-3-methoxy-6-methylanthraquinone \| 1,...) Show SMILES COc1cc(O)c2C(=O)c3c(O)cc(C)cc3C(=O)c2c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.85E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Padova Curated by ChEMBL					Assay Description Inhibition of rat liver cytosolic TrxR1 by spectrophotometry				Bioorg Med Chem 19: 631-41 (2011) Article DOI: 10.1016/j.bmc.2010.10.045 BindingDB Entry DOI: 10.7270/Q25D8S4N
University of Padova Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50005886 (1,8-Dihydroxy-3-methoxy-6-methylanthraquinone \| 1,...) Show SMILES COc1cc(O)c2C(=O)c3c(O)cc(C)cc3C(=O)c2c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.81E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of p56 lck				J Nat Prod 55: 1529-1560 (1992) Article DOI: 10.1021/np50089a001 BindingDB Entry DOI: 10.7270/Q2J966CC
TBA Curated by ChEMBL					More data for this Ligand-Target Pair