BindingDB PrimarySearch

Found 7 hits of ic50 for monomerid = 50008072
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50008072 ((+)-pilocarpine \| (3S,4R)-3-ethyl-4-[(1-methyl-1H-...) Show SMILES CC[C@H]1[C@@H](Cc2cncn2C)COC1=O \|r\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligand				Bioorg Med Chem Lett 8: 2897-902 (1999) BindingDB Entry DOI: 10.7270/Q27M08GK
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50008072 ((+)-pilocarpine \| (3S,4R)-3-ethyl-4-[(1-methyl-1H-...) Show SMILES CC[C@H]1[C@@H](Cc2cncn2C)COC1=O \|r\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Sandoz Pharma Ltd. Curated by ChEMBL					Assay Description Central presynaptic activity as effect on electrically evoked acetylcholine release from rat hippocampal slices (M2 model)				J Med Chem 35: 15-27 (1992) BindingDB Entry DOI: 10.7270/Q29022RV
Sandoz Pharma Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50008072 ((+)-pilocarpine \| (3S,4R)-3-ethyl-4-[(1-methyl-1H-...) Show SMILES CC[C@H]1[C@@H](Cc2cncn2C)COC1=O \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
Sandoz Pharma Ltd. Curated by ChEMBL					Assay Description Ability to displace [3H]-pirenzepine (pir) from muscarinic acetylcholine receptor M1 in rat cortical tissue.				J Med Chem 35: 15-27 (1992) BindingDB Entry DOI: 10.7270/Q29022RV
Sandoz Pharma Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50008072 ((+)-pilocarpine \| (3S,4R)-3-ethyl-4-[(1-methyl-1H-...) Show SMILES CC[C@H]1[C@@H](Cc2cncn2C)COC1=O \|r\| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article	n/a	n/a	4.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for the displacement of the muscarinic QNB in a genetically transformed rat cell line (m1c2) transfected with cloned m1 recept...				Bioorg Med Chem Lett 1: 147-150 (1991) Article DOI: 10.1016/S0960-894X(01)80787-3 BindingDB Entry DOI: 10.7270/Q2513Z3K
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50008072 ((+)-pilocarpine \| (3S,4R)-3-ethyl-4-[(1-methyl-1H-...) Show SMILES CC[C@H]1[C@@H](Cc2cncn2C)COC1=O \|r\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Toledo Curated by ChEMBL					Assay Description Inhibition of [3H]-(R)-QNB binding to muscarinic receptors of rat brain membranes.				J Med Chem 36: 842-7 (1993) Article DOI: 10.1021/jm00059a008 BindingDB Entry DOI: 10.7270/Q26H4M4D
University of Toledo Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5 (RAT)	BDBM50008072 ((+)-pilocarpine \| (3S,4R)-3-ethyl-4-[(1-methyl-1H-...) Show SMILES CC[C@H]1[C@@H](Cc2cncn2C)COC1=O \|r\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars		n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity at 5-hydroxytryptamine 3 receptor in rat posterior cortex by [3H]-BRL 43694 displacement.				Citation and Details BindingDB Entry DOI: 10.7270/Q24M96PX
TBA					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50008072 ((+)-pilocarpine \| (3S,4R)-3-ethyl-4-[(1-methyl-1H-...) Show SMILES CC[C@H]1[C@@H](Cc2cncn2C)COC1=O \|r\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for the displacement of the muscarinic QNB in rat heart homogenate containing the pharmacologic M2 receptor (M2-QNB heart)				Bioorg Med Chem Lett 1: 147-150 (1991) Article DOI: 10.1016/S0960-894X(01)80787-3 BindingDB Entry DOI: 10.7270/Q2513Z3K
TBA Curated by ChEMBL					More data for this Ligand-Target Pair