Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50017305   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50017305 (CHEMBL3287992) Show SMILES OCc1nc(cs1)C(=O)N[C@H]1CC[C@H](CC1)NC(=O)c1cc(F)cnc1Oc1cccc(c1)-c1ccc(O)cc1CN1CCOCC1 |r,wU:10.10,13.17,(22.02,-3.74,;21.3,-5.09,;19.76,-5.14,;18.89,-6.41,;17.41,-5.97,;17.36,-4.44,;18.81,-3.92,;16.2,-6.92,;16.2,-8.46,;14.86,-6.14,;13.52,-6.92,;13.52,-8.46,;12.19,-9.22,;10.85,-8.45,;10.85,-6.92,;12.18,-6.14,;9.52,-9.22,;8.18,-8.46,;8.18,-6.92,;6.85,-9.23,;5.52,-8.47,;4.18,-9.24,;2.85,-8.47,;4.18,-10.78,;5.52,-11.56,;6.86,-10.78,;8.19,-11.56,;8.2,-13.1,;6.86,-13.86,;6.86,-15.4,;8.2,-16.18,;9.54,-15.39,;9.53,-13.85,;10.87,-16.15,;10.88,-17.7,;12.21,-18.46,;13.54,-17.68,;14.88,-18.44,;13.53,-16.13,;12.19,-15.37,;12.18,-13.83,;13.51,-13.06,;14.84,-13.82,;16.17,-13.05,;16.16,-11.51,;14.83,-10.75,;13.49,-11.52,)| Show InChI InChI=1S/C34H36FN5O6S/c35-23-16-29(32(43)37-24-4-6-25(7-5-24)38-33(44)30-20-47-31(19-41)39-30)34(36-17-23)46-27-3-1-2-21(15-27)28-9-8-26(42)14-22(28)18-40-10-12-45-13-11-40/h1-3,8-9,14-17,20,24-25,41-42H,4-7,10-13,18-19H2,(H,37,43)(H,38,44)/t24-,25+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.0631	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4B using [3H]cAMP by packard topcount scintillation counting analysis				J Med Chem 57: 4661-76 (2014) Article DOI: 10.1021/jm5001216 BindingDB Entry DOI: 10.7270/Q2708302
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