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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50033995   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sterol O-acyltransferase 1


(Rattus norvegicus)		BDBM50033995
PNG
(3-(2,4-Difluoro-phenyl)-1-heptyl-1-[5-(1H-8-oxa-1,...)
Show SMILES CCCCCCCN(CCCCCSc1nc-2c([nH]1)-c1ccccc1Oc1ccccc-21)C(=O)Nc1ccc(F)cc1F
Show InChI InChI=1S/C34H38F2N4O2S/c1-2-3-4-5-11-20-40(34(41)37-28-19-18-24(35)23-27(28)36)21-12-6-13-22-43-33-38-31-25-14-7-9-16-29(25)42-30-17-10-8-15-26(30)32(31)39-33/h7-10,14-19,23H,2-6,11-13,20-22H2,1H3,(H,37,41)(H,38,39)
PDB

KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 60n/an/an/an/an/an/a



DuPont Merck Research Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.

J Med Chem 38: 1067-83 (1995)


BindingDB Entry DOI: 10.7270/Q28S4P0T
More data for this
Ligand-Target Pair