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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 50043359   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-lipoxygenase


(Bos taurus)		BDBM50043359
PNG
(1,8-Dihydroxy-10-[2-(4-hydroxy-phenyl)-acetyl]-10H...)
Show SMILES Oc1ccc(CC(=O)C2c3cccc(O)c3C(=O)c3c(O)cccc23)cc1
Show InChI InChI=1S/C22H16O5/c23-13-9-7-12(8-10-13)11-18(26)19-14-3-1-5-16(24)20(14)22(27)21-15(19)4-2-6-17(21)25/h1-10,19,23-25H,11H2
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n/an/a 2.00E+3n/an/an/an/an/an/a



Universität Regensburg

Curated by ChEMBL


Assay Description
Tested for the inhibition of lipid peroxidation in bovine brain phospholipid liposomes

J Med Chem 36: 4099-107 (1994)


BindingDB Entry DOI: 10.7270/Q2G44PC2
More data for this
Ligand-Target Pair
5-lipoxygenase


(Bos taurus)		BDBM50043359
PNG
(1,8-Dihydroxy-10-[2-(4-hydroxy-phenyl)-acetyl]-10H...)
Show SMILES Oc1ccc(CC(=O)C2c3cccc(O)c3C(=O)c3c(O)cccc23)cc1
Show InChI InChI=1S/C22H16O5/c23-13-9-7-12(8-10-13)11-18(26)19-14-3-1-5-16(24)20(14)22(27)21-15(19)4-2-6-17(21)25/h1-10,19,23-25H,11H2
PDB
MMDB

Reactome pathway

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a 1.40E+4n/an/an/an/an/an/a



Universität Regensburg

Curated by ChEMBL


Assay Description
Inhibitory activity against 5-lipoxygenase (inhibition of 5-HETE and LTB4 biosynthesis) in bovine polymorphonuclear leukocytes (PMNL).

J Med Chem 36: 4099-107 (1994)


BindingDB Entry DOI: 10.7270/Q2G44PC2
More data for this
Ligand-Target Pair