BindingDB PrimarySearch

Found 7 hits of ic50 for monomerid = 50074745
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50074745 (3-(3-Chloro-phenyl)-5,7-dihydroxy-chromen-4-one \| ...) Show SMILES Oc1cc(O)c2c(c1)occ(-c1cccc(Cl)c1)c2=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Limited Curated by ChEMBL					Assay Description Inhibition of Epidermal growth factor receptor				J Med Chem 42: 1018-26 (1999) Article DOI: 10.1021/jm980551o BindingDB Entry DOI: 10.7270/Q21835PV
NOVARTIS Limited Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Homo sapiens (Human))	BDBM50074745 (3-(3-Chloro-phenyl)-5,7-dihydroxy-chromen-4-one \| ...) Show SMILES Oc1cc(O)c2c(c1)occ(-c1cccc(Cl)c1)c2=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Limited Curated by ChEMBL					Assay Description Inhibition of Platelet-derived growth factor receptor-dependent phosphorylation				J Med Chem 42: 1018-26 (1999) Article DOI: 10.1021/jm980551o BindingDB Entry DOI: 10.7270/Q21835PV
NOVARTIS Limited Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50074745 (3-(3-Chloro-phenyl)-5,7-dihydroxy-chromen-4-one \| ...) Show SMILES Oc1cc(O)c2c(c1)occ(-c1cccc(Cl)c1)c2=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Limited Curated by ChEMBL					Assay Description Inhibition of Epidermal growth factor receptor-dependent phosphorylation				J Med Chem 42: 1018-26 (1999) Article DOI: 10.1021/jm980551o BindingDB Entry DOI: 10.7270/Q21835PV
NOVARTIS Limited Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Mus musculus)	BDBM50074745 (3-(3-Chloro-phenyl)-5,7-dihydroxy-chromen-4-one \| ...) Show SMILES Oc1cc(O)c2c(c1)occ(-c1cccc(Cl)c1)c2=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Limited Curated by ChEMBL					Assay Description Inhibition of EGF-dependent mouse keratinocyte MK cell proliferation				J Med Chem 42: 1018-26 (1999) Article DOI: 10.1021/jm980551o BindingDB Entry DOI: 10.7270/Q21835PV
NOVARTIS Limited Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1/ABL2 (Homo sapiens (Human))	BDBM50074745 (3-(3-Chloro-phenyl)-5,7-dihydroxy-chromen-4-one \| ...) Show SMILES Oc1cc(O)c2c(c1)occ(-c1cccc(Cl)c1)c2=O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Limited Curated by ChEMBL					Assay Description Inhibition of v-Abl tyrosine kinase				J Med Chem 42: 1018-26 (1999) Article DOI: 10.1021/jm980551o BindingDB Entry DOI: 10.7270/Q21835PV
NOVARTIS Limited Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50074745 (3-(3-Chloro-phenyl)-5,7-dihydroxy-chromen-4-one \| ...) Show SMILES Oc1cc(O)c2c(c1)occ(-c1cccc(Cl)c1)c2=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Limited Curated by ChEMBL					Assay Description Inhibition of Protein kinase C alpha				J Med Chem 42: 1018-26 (1999) Article DOI: 10.1021/jm980551o BindingDB Entry DOI: 10.7270/Q21835PV
NOVARTIS Limited Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50074745 (3-(3-Chloro-phenyl)-5,7-dihydroxy-chromen-4-one \| ...) Show SMILES Oc1cc(O)c2c(c1)occ(-c1cccc(Cl)c1)c2=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Limited Curated by ChEMBL					Assay Description Inhibition of p60 c-Src tyrosine kinase				J Med Chem 42: 1018-26 (1999) Article DOI: 10.1021/jm980551o BindingDB Entry DOI: 10.7270/Q21835PV
NOVARTIS Limited Curated by ChEMBL					More data for this Ligand-Target Pair