Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM50074933 (2-biphenyl-4-yl-propionic acid | CHEMBL317434 | al...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada Inc. Curated by ChEMBL | Assay Description In vitro inhibitory activity against Prostaglandin G/H synthase 1 in sheep | Bioorg Med Chem Lett 9: 307-12 (1999) BindingDB Entry DOI: 10.7270/Q2H994CC | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50074933 (2-biphenyl-4-yl-propionic acid | CHEMBL317434 | al...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Canada Inc. Curated by ChEMBL | Assay Description In vitro inhibitory activity against Prostaglandin G/H synthase 2 (COX-2) in human | Bioorg Med Chem Lett 9: 307-12 (1999) BindingDB Entry DOI: 10.7270/Q2H994CC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM50074933 (2-biphenyl-4-yl-propionic acid | CHEMBL317434 | al...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Drexel University College of Medicine Curated by ChEMBL | Assay Description Reverisible competitive inhibition of prostaglandin G/H synthase 1 | Bioorg Med Chem Lett 14: 667-71 (2004) BindingDB Entry DOI: 10.7270/Q2N29WC9 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM50074933 (2-biphenyl-4-yl-propionic acid | CHEMBL317434 | al...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
King's College London Curated by ChEMBL | Assay Description Inhibition of ovine COX1 | Bioorg Med Chem 18: 2204-18 (2010) Article DOI: 10.1016/j.bmc.2010.01.070 BindingDB Entry DOI: 10.7270/Q27945MJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |