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Compile Data Set for Download or QSAR

Found 4 hits of ic50 for monomerid = 50078834   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Methionine aminopeptidase


(Escherichia coli (strain K12))
BDBM50078834
PNG
(2-(pyridin-2-yl)-1H-benzo[d]imidazole | 2-pyridin-...)
Show SMILES c1ccc(nc1)-c1nc2ccccc2[nH]1
Show InChI InChI=1S/C12H9N3/c1-2-6-10-9(5-1)14-12(15-10)11-7-3-4-8-13-11/h1-8H,(H,14,15)
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Article
PubMed
n/an/a 574n/an/an/an/an/an/a



Saarland University

Curated by ChEMBL


Assay Description
Inhibition of Co2+ loaded MetAP expressed in Escherichia coli


J Med Chem 49: 511-22 (2006)


Article DOI: 10.1021/jm050476z
BindingDB Entry DOI: 10.7270/Q2N58KXD
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (Human))
BDBM50078834
PNG
(2-(pyridin-2-yl)-1H-benzo[d]imidazole | 2-pyridin-...)
Show SMILES c1ccc(nc1)-c1nc2ccccc2[nH]1
Show InChI InChI=1S/C12H9N3/c1-2-6-10-9(5-1)14-12(15-10)11-7-3-4-8-13-11/h1-8H,(H,14,15)
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n/an/a 1.33E+4n/an/an/an/an/an/a



Universit£t Heidelberg

Curated by ChEMBL


Assay Description
Inhibition of human MetAP2 expressed in baculovirus infected Sf9 cells


Bioorg Med Chem Lett 20: 4038-44 (2010)


Article DOI: 10.1016/j.bmcl.2010.05.093
BindingDB Entry DOI: 10.7270/Q2RF5W0K
More data for this
Ligand-Target Pair
Methionine aminopeptidase 1


(Homo sapiens (Human))
BDBM50078834
PNG
(2-(pyridin-2-yl)-1H-benzo[d]imidazole | 2-pyridin-...)
Show SMILES c1ccc(nc1)-c1nc2ccccc2[nH]1
Show InChI InChI=1S/C12H9N3/c1-2-6-10-9(5-1)14-12(15-10)11-7-3-4-8-13-11/h1-8H,(H,14,15)
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Article
PubMed
n/an/a 2.84E+4n/an/an/an/an/an/a



Universit£t Heidelberg

Curated by ChEMBL


Assay Description
Inhibition of human MetAP1


Bioorg Med Chem Lett 20: 4038-44 (2010)


Article DOI: 10.1016/j.bmcl.2010.05.093
BindingDB Entry DOI: 10.7270/Q2RF5W0K
More data for this
Ligand-Target Pair
Cytochrome P450 2B1


(Rattus norvegicus)
BDBM50078834
PNG
(2-(pyridin-2-yl)-1H-benzo[d]imidazole | 2-pyridin-...)
Show SMILES c1ccc(nc1)-c1nc2ccccc2[nH]1
Show InChI InChI=1S/C12H9N3/c1-2-6-10-9(5-1)14-12(15-10)11-7-3-4-8-13-11/h1-8H,(H,14,15)
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n/an/a 6.46E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats.


J Med Chem 25: 887-92 (1982)


BindingDB Entry DOI: 10.7270/Q2VT1T8J
More data for this
Ligand-Target Pair