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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50084013   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proteasome subunit beta type-5


(Homo sapiens (Human))
BDBM50084013
PNG
(CHEMBL3423346)
Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)Cc1cccc(Oc2ccccc2)c1)C(=O)NCCO |r|
Show InChI InChI=1S/C25H32N4O6/c1-16(2)23(25(34)27-11-12-30)29-24(33)20(15-21(26)31)28-22(32)14-17-7-6-10-19(13-17)35-18-8-4-3-5-9-18/h3-10,13,16,20,23,30H,11-12,14-15H2,1-2H3,(H2,26,31)(H,27,34)(H,28,32)(H,29,33)/t20-,23-/m0/s1
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Similars

Article
PubMed
n/an/a 1.72E+4n/an/an/an/an/an/a



Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL


Assay Description
Inhibition of chymotrypsin-like activity of human beta-5 subunit of 20S proteasome using Suc-LLVY-AMC as substrate by fluorometer analysis


Eur J Med Chem 98: 61-8 (2015)


Article DOI: 10.1016/j.ejmech.2015.05.023
BindingDB Entry DOI: 10.7270/Q228099R
More data for this
Ligand-Target Pair