BDBM50084013 CHEMBL3423346

SMILES: CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)Cc1cccc(Oc2ccccc2)c1)C(=O)NCCO

InChI Key: InChIKey=GUQKWJXFDYMMGI-REWPJTCUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50084013   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
20S proteasome chymotrypsin-like (Homo sapiens (Human))	BDBM50084013 (CHEMBL3423346) Show SMILES CC(C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)Cc1cccc(Oc2ccccc2)c1)C(=O)NCCO |r| Show InChI InChI=1S/C25H32N4O6/c1-16(2)23(25(34)27-11-12-30)29-24(33)20(15-21(26)31)28-22(32)14-17-7-6-10-19(13-17)35-18-8-4-3-5-9-18/h3-10,13,16,20,23,30H,11-12,14-15H2,1-2H3,(H2,26,31)(H,27,34)(H,28,32)(H,29,33)/t20-,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.72E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of human beta-5 subunit of 20S proteasome using Suc-LLVY-AMC as substrate by fluorometer analysis				Eur J Med Chem 98: 61-8 (2015) Article DOI: 10.1016/j.ejmech.2015.05.023 BindingDB Entry DOI: 10.7270/Q228099R
					More data for this Ligand-Target Pair