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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50097485   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))
BDBM50097485
PNG
(CHEMBL3585872)
Show SMILES CC1CN(CC(C)O1)NCC(O)CO\N=C\c1ccc(OC(F)F)c(OC2CCCC2)c1
Show InChI InChI=1S/C22H33F2N3O5/c1-15-12-27(13-16(2)30-15)25-11-18(28)14-29-26-10-17-7-8-20(32-22(23)24)21(9-17)31-19-5-3-4-6-19/h7-10,15-16,18-19,22,25,28H,3-6,11-14H2,1-2H3/b26-10+
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PC sid
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Similars

Article
PubMed
n/an/a 190n/an/an/an/an/an/a



University of Genoa

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDE4D3 expressed in baculoviral system using cAMP as substrate by fluorescence polarization assay


Bioorg Med Chem 23: 3426-35 (2015)


Article DOI: 10.1016/j.bmc.2015.04.027
BindingDB Entry DOI: 10.7270/Q2NC62ZZ
More data for this
Ligand-Target Pair