Compile Data Set for Download or QSAR

Found 6 hits of ic50 for monomerid = 50107241   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4-kinase beta (Homo sapiens (Human))	BDBM50107241 (CHEMBL3600777) Show SMILES Cn1ccc(cc1=O)-c1ccc2nc(N)sc2c1 Show InChI InChI=1S/C13H11N3OS/c1-16-5-4-9(7-12(16)17)8-2-3-10-11(6-8)18-13(14)15-10/h2-7H,1H3,(H2,14,15)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human full length recombinant PI4K3beta expressed in Sf9 cells using D-myo-phosphatidylinositol substrate and ATP...				Bioorg Med Chem Lett 25: 3189-93 (2015) Article DOI: 10.1016/j.bmcl.2015.05.093 BindingDB Entry DOI: 10.7270/Q2KK9DKR
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-kinase alpha (Homo sapiens (Human))	BDBM50107241 (CHEMBL3600777) Show SMILES Cn1ccc(cc1=O)-c1ccc2nc(N)sc2c1 Show InChI InChI=1S/C13H11N3OS/c1-16-5-4-9(7-12(16)17)8-2-3-10-11(6-8)18-13(14)15-10/h2-7H,1H3,(H2,14,15)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of N-terminal FLAG-tagged human full length recombinant PI4K3alpha using D-myo-phosphatidylinositol substrate and ATP incubated for 45 min...				Bioorg Med Chem Lett 25: 3189-93 (2015) Article DOI: 10.1016/j.bmcl.2015.05.093 BindingDB Entry DOI: 10.7270/Q2KK9DKR
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50107241 (CHEMBL3600777) Show SMILES Cn1ccc(cc1=O)-c1ccc2nc(N)sc2c1 Show InChI InChI=1S/C13H11N3OS/c1-16-5-4-9(7-12(16)17)8-2-3-10-11(6-8)18-13(14)15-10/h2-7H,1H3,(H2,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) pre-incubated for 20 mins before phosphatidylinositol 4, 5-bisphosphate substrate addition by kinase-glo plu...				Bioorg Med Chem Lett 25: 3189-93 (2015) Article DOI: 10.1016/j.bmcl.2015.05.093 BindingDB Entry DOI: 10.7270/Q2KK9DKR
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50107241 (CHEMBL3600777) Show SMILES Cn1ccc(cc1=O)-c1ccc2nc(N)sc2c1 Show InChI InChI=1S/C13H11N3OS/c1-16-5-4-9(7-12(16)17)8-2-3-10-11(6-8)18-13(14)15-10/h2-7H,1H3,(H2,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin) pre-incubated for 20 mins before phosphatidylinositol 4, 5-bisphosphate substrate addition by kinase-glo plu...				Bioorg Med Chem Lett 25: 3189-93 (2015) Article DOI: 10.1016/j.bmcl.2015.05.093 BindingDB Entry DOI: 10.7270/Q2KK9DKR
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50107241 (CHEMBL3600777) Show SMILES Cn1ccc(cc1=O)-c1ccc2nc(N)sc2c1 Show InChI InChI=1S/C13H11N3OS/c1-16-5-4-9(7-12(16)17)8-2-3-10-11(6-8)18-13(14)15-10/h2-7H,1H3,(H2,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PI3Kbeta (unknown origin) pre-incubated for 20 mins before phosphatidylinositol 4, 5-bisphosphate substrate addition by kinase-glo plus...				Bioorg Med Chem Lett 25: 3189-93 (2015) Article DOI: 10.1016/j.bmcl.2015.05.093 BindingDB Entry DOI: 10.7270/Q2KK9DKR
					More data for this Ligand-Target Pair
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma (Homo sapiens (Human))	BDBM50107241 (CHEMBL3600777) Show SMILES Cn1ccc(cc1=O)-c1ccc2nc(N)sc2c1 Show InChI InChI=1S/C13H11N3OS/c1-16-5-4-9(7-12(16)17)8-2-3-10-11(6-8)18-13(14)15-10/h2-7H,1H3,(H2,14,15)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PIP5K1C (unknown origin) using D-myo-phosphatidylinositol 4-phosphate substrate and ATP by ADP-Glo kinase Assay				Bioorg Med Chem Lett 25: 3189-93 (2015) Article DOI: 10.1016/j.bmcl.2015.05.093 BindingDB Entry DOI: 10.7270/Q2KK9DKR
					More data for this Ligand-Target Pair