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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50110768   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bifunctional dihydrofolate reductase-thymidylate synthase


(Plasmodium falciparum (isolate K1 / Thailand))		BDBM50110768
PNG
(5-[4-(2,4-Dichloro-benzyloxy)-3-methoxy-phenyl]-6-...)
Show SMILES CCc1nc(N)nc(N)c1-c1ccc(OCc2ccc(Cl)cc2Cl)c(OC)c1
Show InChI InChI=1S/C20H20Cl2N4O2/c1-3-15-18(19(23)26-20(24)25-15)11-5-7-16(17(8-11)27-2)28-10-12-4-6-13(21)9-14(12)22/h4-9H,3,10H2,1-2H3,(H4,23,24,25,26)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



National Center for Genetic Engineering and Biotechnology

Curated by ChEMBL


Assay Description
Antiplasmodial activity (IC50) against Plasmodium falciparum Clone with mutant enzyme C59R+S108N- pfDihydrofolate reductase (K1CB1)

J Med Chem 45: 1244-52 (2002)


BindingDB Entry DOI: 10.7270/Q2Z89BQ1
More data for this
Ligand-Target Pair