Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cathepsin S (Homo sapiens (Human)) | BDBM50121039 (CHEMBL114410 | [(S)-2-Cyclohexyl-1-((5S,6R)-4,4,7-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
currently NAEJA Pharmaceutical Inc. Curated by ChEMBL | Assay Description In vitro Inhibitory activity of the compound was determined against Cathepsin S cysteine protease by using Cbz-Val-Arg-AMC | Bioorg Med Chem Lett 12: 3417-9 (2002) BindingDB Entry DOI: 10.7270/Q280520T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Procathepsin L (Rattus norvegicus) | BDBM50121039 (CHEMBL114410 | [(S)-2-Cyclohexyl-1-((5S,6R)-4,4,7-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
currently NAEJA Pharmaceutical Inc. Curated by ChEMBL | Assay Description Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin L cysteine protease | Bioorg Med Chem Lett 12: 3417-9 (2002) BindingDB Entry DOI: 10.7270/Q280520T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cathepsin K (Homo sapiens (Human)) | BDBM50121039 (CHEMBL114410 | [(S)-2-Cyclohexyl-1-((5S,6R)-4,4,7-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 7.60 | n/a | n/a | n/a | n/a | n/a | n/a |
currently NAEJA Pharmaceutical Inc. Curated by ChEMBL | Assay Description Inhibition of Cbz-Phe-Arg-AMC binding to Cathepsin K cysteine protease | Bioorg Med Chem Lett 12: 3417-9 (2002) BindingDB Entry DOI: 10.7270/Q280520T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cathepsin B (Homo sapiens (Human)) | BDBM50121039 (CHEMBL114410 | [(S)-2-Cyclohexyl-1-((5S,6R)-4,4,7-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 430 | n/a | n/a | n/a | n/a | n/a | n/a |
currently NAEJA Pharmaceutical Inc. Curated by ChEMBL | Assay Description Inhibitory activity of Cbz-Phe-Arg-AMC against Cathepsin B cysteine protease | Bioorg Med Chem Lett 12: 3417-9 (2002) BindingDB Entry DOI: 10.7270/Q280520T | |||||||||||
More data for this Ligand-Target Pair |