Found 4 hits of ic50 for monomerid = 50130511 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Sodium channel protein type 9 subunit alpha
(Homo sapiens (Human)) | BDBM50130511
(CHEMBL3634321)Show SMILES OC(COc1ccccc1C(=O)c1ccccc1)CN1CCN(CC1)c1cccc2NC(=O)COc12 Show InChI InChI=1S/C28H29N3O5/c32-21(18-35-25-12-5-4-9-22(25)27(34)20-7-2-1-3-8-20)17-30-13-15-31(16-14-30)24-11-6-10-23-28(24)36-19-26(33)29-23/h1-12,21,32H,13-19H2,(H,29,33) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human NaV1.7 by IonWorks quattro automated electrophysiology assay |
Bioorg Med Chem Lett 25: 5419-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.09.005
BindingDB Entry DOI: 10.7270/Q2930W06 |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 9 subunit alpha
(Mus musculus) | BDBM50130511
(CHEMBL3634321)Show SMILES OC(COc1ccccc1C(=O)c1ccccc1)CN1CCN(CC1)c1cccc2NC(=O)COc12 Show InChI InChI=1S/C28H29N3O5/c32-21(18-35-25-12-5-4-9-22(25)27(34)20-7-2-1-3-8-20)17-30-13-15-31(16-14-30)24-11-6-10-23-28(24)36-19-26(33)29-23/h1-12,21,32H,13-19H2,(H,29,33) | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of mouse NaV1.7 by IonWorks quattro automated electrophysiology assay |
Bioorg Med Chem Lett 25: 5419-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.09.005
BindingDB Entry DOI: 10.7270/Q2930W06 |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 5 subunit alpha
(Homo sapiens (Human)) | BDBM50130511
(CHEMBL3634321)Show SMILES OC(COc1ccccc1C(=O)c1ccccc1)CN1CCN(CC1)c1cccc2NC(=O)COc12 Show InChI InChI=1S/C28H29N3O5/c32-21(18-35-25-12-5-4-9-22(25)27(34)20-7-2-1-3-8-20)17-30-13-15-31(16-14-30)24-11-6-10-23-28(24)36-19-26(33)29-23/h1-12,21,32H,13-19H2,(H,29,33) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human NaV1.5 by IonWorks quattro automated electrophysiology assay |
Bioorg Med Chem Lett 25: 5419-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.09.005
BindingDB Entry DOI: 10.7270/Q2930W06 |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 1 subunit alpha
(Homo sapiens (Human)) | BDBM50130511
(CHEMBL3634321)Show SMILES OC(COc1ccccc1C(=O)c1ccccc1)CN1CCN(CC1)c1cccc2NC(=O)COc12 Show InChI InChI=1S/C28H29N3O5/c32-21(18-35-25-12-5-4-9-22(25)27(34)20-7-2-1-3-8-20)17-30-13-15-31(16-14-30)24-11-6-10-23-28(24)36-19-26(33)29-23/h1-12,21,32H,13-19H2,(H,29,33) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human NaV1.1 by IonWorks quattro automated electrophysiology assay |
Bioorg Med Chem Lett 25: 5419-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.09.005
BindingDB Entry DOI: 10.7270/Q2930W06 |
More data for this
Ligand-Target Pair | |
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