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Compile Data Set for Download or QSAR

Found 3 hits of ic50 for monomerid = 50140714   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phenylalanine--tRNA ligase alpha subunit


(Streptococcus pyogenes serotype M18)
BDBM50140714
PNG
(CHEMBL27142 | methyl 5-(3,4-dichlorophenyl)-4,6-di...)
Show SMILES COC(=O)C1NC(c2c(O)n(c(O)c12)-c1ccc(Cl)c(Cl)c1)c1ccccc1
Show InChI InChI=1S/C20H16Cl2N2O4/c1-28-20(27)17-15-14(16(23-17)10-5-3-2-4-6-10)18(25)24(19(15)26)11-7-8-12(21)13(22)9-11/h2-9,16-17,23,25-26H,1H3
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Article
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n/an/a>1.00E+5n/an/an/an/an/an/a



Cubist Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against phenylalanyl-tRNA synthetase from Staphylococcus aureus


Bioorg Med Chem Lett 14: 1339-42 (2004)


Article DOI: 10.1016/j.bmcl.2003.11.081
BindingDB Entry DOI: 10.7270/Q2PR7VDS
More data for this
Ligand-Target Pair
Phenylalanine--tRNA ligase alpha subunit


(Streptococcus pyogenes serotype M18)
BDBM50140714
PNG
(CHEMBL27142 | methyl 5-(3,4-dichlorophenyl)-4,6-di...)
Show SMILES COC(=O)C1NC(c2c(O)n(c(O)c12)-c1ccc(Cl)c(Cl)c1)c1ccccc1
Show InChI InChI=1S/C20H16Cl2N2O4/c1-28-20(27)17-15-14(16(23-17)10-5-3-2-4-6-10)18(25)24(19(15)26)11-7-8-12(21)13(22)9-11/h2-9,16-17,23,25-26H,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

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Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Cubist Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against phenylalanyl-tRNA synthetase from Enterococcus faecalis


Bioorg Med Chem Lett 14: 1339-42 (2004)


Article DOI: 10.1016/j.bmcl.2003.11.081
BindingDB Entry DOI: 10.7270/Q2PR7VDS
More data for this
Ligand-Target Pair
Phenylalanine--tRNA ligase, mitochondrial


(Homo sapiens (Human))
BDBM50140714
PNG
(CHEMBL27142 | methyl 5-(3,4-dichlorophenyl)-4,6-di...)
Show SMILES COC(=O)C1NC(c2c(O)n(c(O)c12)-c1ccc(Cl)c(Cl)c1)c1ccccc1
Show InChI InChI=1S/C20H16Cl2N2O4/c1-28-20(27)17-15-14(16(23-17)10-5-3-2-4-6-10)18(25)24(19(15)26)11-7-8-12(21)13(22)9-11/h2-9,16-17,23,25-26H,1H3
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UniProtKB/SwissProt

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GoogleScholar
AffyNet 
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PC cid
PC sid
UniChem

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Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Cubist Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against human phenylalanyl-tRNA synthetase was determined


Bioorg Med Chem Lett 14: 1339-42 (2004)


Article DOI: 10.1016/j.bmcl.2003.11.081
BindingDB Entry DOI: 10.7270/Q2PR7VDS
More data for this
Ligand-Target Pair