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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50142529   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA topoisomerase 1


(Homo sapiens (Human))		BDBM50142529
PNG
(Acetic acid 2,3-diacetoxy-5-[2-(3,4,5-triacetoxy-b...)
Show SMILES CC(=O)Oc1cc(cc(OC(C)=O)c1OC(C)=O)C(=O)Nc1ccccc1NC(=O)c1cc(OC(C)=O)c(OC(C)=O)c(OC(C)=O)c1
Show InChI InChI=1S/C32H28N2O14/c1-15(35)43-25-11-21(12-26(44-16(2)36)29(25)47-19(5)39)31(41)33-23-9-7-8-10-24(23)34-32(42)22-13-27(45-17(3)37)30(48-20(6)40)28(14-22)46-18(4)38/h7-14H,1-6H3,(H,33,41)(H,34,42)
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 4.70E+3n/an/an/an/an/an/a



Kumamoto University

Curated by ChEMBL


Assay Description
Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed form

Bioorg Med Chem Lett 14: 1669-72 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.060
BindingDB Entry DOI: 10.7270/Q2GX4B0X
More data for this
Ligand-Target Pair