Compile Data Set for Download or QSAR

Found 4 hits of ic50 for monomerid = 50151357   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50151357 (2-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyri...) Show SMILES c1[nH]nc(c1-c1ccc2ncccc2n1)-c1ccccn1 Show InChI InChI=1S/C16H11N5/c1-2-8-18-15(4-1)16-11(10-19-21-16)12-6-7-13-14(20-12)5-3-9-17-13/h1-10H,(H,19,21)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of recombinant Activin A receptor type II-like kinase (ALK5) expressed in baculovirus/Sf9 cells				J Med Chem 47: 4494-506 (2004) Article DOI: 10.1021/jm0400247 BindingDB Entry DOI: 10.7270/Q2VQ325T
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50151357 (2-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyri...) Show SMILES c1[nH]nc(c1-c1ccc2ncccc2n1)-c1ccccn1 Show InChI InChI=1S/C16H11N5/c1-2-8-18-15(4-1)16-11(10-19-21-16)12-6-7-13-14(20-12)5-3-9-17-13/h1-10H,(H,19,21)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of TGFR1				Eur J Med Chem 44: 4259-65 (2009) Article DOI: 10.1016/j.ejmech.2009.07.008 BindingDB Entry DOI: 10.7270/Q2BC3ZM9
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50151357 (2-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyri...) Show SMILES c1[nH]nc(c1-c1ccc2ncccc2n1)-c1ccccn1 Show InChI InChI=1S/C16H11N5/c1-2-8-18-15(4-1)16-11(10-19-21-16)12-6-7-13-14(20-12)5-3-9-17-13/h1-10H,(H,19,21)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity to Activin A receptor type II-like kinase (ALK5) in fluorescence polarization binding assay; Range is (0.029-0.032)				J Med Chem 47: 4494-506 (2004) Article DOI: 10.1021/jm0400247 BindingDB Entry DOI: 10.7270/Q2VQ325T
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50151357 (2-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyri...) Show SMILES c1[nH]nc(c1-c1ccc2ncccc2n1)-c1ccccn1 Show InChI InChI=1S/C16H11N5/c1-2-8-18-15(4-1)16-11(10-19-21-16)12-6-7-13-14(20-12)5-3-9-17-13/h1-10H,(H,19,21)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Stimulation of Transforming growth factor beta receptor I kinase in HepG2 cells				J Med Chem 47: 4494-506 (2004) Article DOI: 10.1021/jm0400247 BindingDB Entry DOI: 10.7270/Q2VQ325T
					More data for this Ligand-Target Pair