Found 2 hits of ic50 for monomerid = 50160860 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
RNA-directed RNA polymerase
(Hepatitis C virus) | BDBM50160860
(CHEMBL2373427 | Fullerene Derivative)Show SMILES [I-].[I-].[H][C@@]12C3=c4c5c6c7c8C(=C9c%10c%11c%12-c%13c%14c%15c%16c%17c%18c(c4c4c5c5c7c7c%19c8[C@]8%20C[N+](C)(C)C[C@]98[C@@]%11([H])[C@]8([H])c%13c9c%11c8c%20c%19c8c%11c%11c(c%159)c%16c9c%18c4c4c9c%11c8c7c54)[C@@]45C[N+](C)(C)C[C@@]34c(c1%10)c%12[C@]%14([H])[C@@]%175[H])[C@@]26[H] |c:2,t:8| Show InChI InChI=1S/C68H26N2/c1-69(2)5-65-57-41-29-17-9-10-14-11-15-23-31(19(11)17)43(41)59(65)49-37(23)28-36-26(15)34-22(14)30-18(10)20-12-13(9)21(29)33-25-16(12)24-32(20)44-42(30)58-46(34)48(36)62-54-39(28)51(49)63-55-53-40-27(35(25)47(45(33)57)61(53)67(63,65)7-69)38(24)50-52(40)64(56(54)55)68(62)8-70(3,4)6-66(58,68)60(44)50/h39,47,50,54,60-61H,5-8H2,1-4H3/q+2/t39-,47+,50?,54-,60+,61-,65+,66?,67-,68-/m0/s1 | PDB
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoritsu University of Pharmacy
Curated by ChEMBL
| Assay Description Inhibitory concentration against Hepatitis C virus-RNA-dependent RNA polymerase |
Bioorg Med Chem Lett 15: 1107-9 (2005)
Article DOI: 10.1016/j.bmcl.2004.12.030 BindingDB Entry DOI: 10.7270/Q29C6WZS |
More data for this Ligand-Target Pair | |
Reverse transcriptase/RNaseH
(Human immunodeficiency virus 1) | BDBM50160860
(CHEMBL2373427 | Fullerene Derivative)Show SMILES [I-].[I-].[H][C@@]12C3=c4c5c6c7c8C(=C9c%10c%11c%12-c%13c%14c%15c%16c%17c%18c(c4c4c5c5c7c7c%19c8[C@]8%20C[N+](C)(C)C[C@]98[C@@]%11([H])[C@]8([H])c%13c9c%11c8c%20c%19c8c%11c%11c(c%159)c%16c9c%18c4c4c9c%11c8c7c54)[C@@]45C[N+](C)(C)C[C@@]34c(c1%10)c%12[C@]%14([H])[C@@]%175[H])[C@@]26[H] |c:2,t:8| Show InChI InChI=1S/C68H26N2/c1-69(2)5-65-57-41-29-17-9-10-14-11-15-23-31(19(11)17)43(41)59(65)49-37(23)28-36-26(15)34-22(14)30-18(10)20-12-13(9)21(29)33-25-16(12)24-32(20)44-42(30)58-46(34)48(36)62-54-39(28)51(49)63-55-53-40-27(35(25)47(45(33)57)61(53)67(63,65)7-69)38(24)50-52(40)64(56(54)55)68(62)8-70(3,4)6-66(58,68)60(44)50/h39,47,50,54,60-61H,5-8H2,1-4H3/q+2/t39-,47+,50?,54-,60+,61-,65+,66?,67-,68-/m0/s1 | PDB MMDB
UniProtKB/TrEMBL
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoritsu University of Pharmacy
Curated by ChEMBL
| Assay Description Inhibitory concentration against HIV-Reverse transcriptase |
Bioorg Med Chem Lett 15: 1107-9 (2005)
Article DOI: 10.1016/j.bmcl.2004.12.030 BindingDB Entry DOI: 10.7270/Q29C6WZS |
More data for this Ligand-Target Pair | |