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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50171338   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Beta-secretase 1


(Homo sapiens (Human))		BDBM50171338
PNG
(5-[3-(3,5-Bis-trifluoromethyl-phenyl)-ureido]-2-di...)
Show SMILES COCCCNC(=O)c1cc(NC(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F)ccc1N(C)C
Show InChI InChI=1S/C22H24F6N4O3/c1-32(2)18-6-5-15(12-17(18)19(33)29-7-4-8-35-3)30-20(34)31-16-10-13(21(23,24)25)9-14(11-16)22(26,27)28/h5-6,9-12H,4,7-8H2,1-3H3,(H,29,33)(H2,30,31,34)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.84E+5n/an/an/an/an/an/a



University of Zürich

Curated by ChEMBL


Assay Description
Inhibitory concentration against beta-site APP cleaving enzyme (BACE-1) by fluorescence resonance energy transfer assay

J Med Chem 48: 5108-11 (2005)


Article DOI: 10.1021/jm050499d
BindingDB Entry DOI: 10.7270/Q228074P
More data for this
Ligand-Target Pair