Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 50177265   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177265 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES Cn1cncc1CCNC(=O)C1CN(CCN1C(=O)NC1CCCCC1)C1c2ccc(Cl)cc2CCc2cc(Br)cnc12 Show InChI InChI=1S/C32H39BrClN7O2/c1-39-20-35-18-26(39)11-12-36-31(42)28-19-40(13-14-41(28)32(43)38-25-5-3-2-4-6-25)30-27-10-9-24(34)16-21(27)7-8-22-15-23(33)17-37-29(22)30/h9-10,15-18,20,25,28,30H,2-8,11-14,19H2,1H3,(H,36,42)(H,38,43)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177265 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES Cn1cncc1CCNC(=O)C1CN(CCN1C(=O)NC1CCCCC1)C1c2ccc(Cl)cc2CCc2cc(Br)cnc12 Show InChI InChI=1S/C32H39BrClN7O2/c1-39-20-35-18-26(39)11-12-36-31(42)28-19-40(13-14-41(28)32(43)38-25-5-3-2-4-6-25)30-27-10-9-24(34)16-21(27)7-8-22-15-23(33)17-37-29(22)30/h9-10,15-18,20,25,28,30H,2-8,11-14,19H2,1H3,(H,36,42)(H,38,43)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against Ha-Ras processing in COS7 cells				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair