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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 50177711   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DNA helicase IV


(Escherichia coli (strain K12))
BDBM50177711
PNG
((5-oxo-5,11-dihydro-10-thia-dibenzo[a,d]cyclohepte...)
Show SMILES OC(=O)Cc1ccc2SCc3ccccc3C(=O)c2c1
Show InChI InChI=1S/C16H12O3S/c17-15(18)8-10-5-6-14-13(7-10)16(19)12-4-2-1-3-11(12)9-20-14/h1-7H,8-9H2,(H,17,18)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 5.00E+3n/an/an/an/an/an/a



Novartis Institutes for Biomedical Research

Curated by ChEMBL


Assay Description
Inhibition of ATPase activity of Helicase4 from Escherichia coli in presence of ATP (5x Km(ATP)) and dT25 (5x KDNA)


Bioorg Med Chem Lett 16: 923-7 (2006)


Article DOI: 10.1016/j.bmcl.2005.10.110
BindingDB Entry DOI: 10.7270/Q2MS3SB8
More data for this
Ligand-Target Pair
DNA helicase IV


(Escherichia coli (strain K12))
BDBM50177711
PNG
((5-oxo-5,11-dihydro-10-thia-dibenzo[a,d]cyclohepte...)
Show SMILES OC(=O)Cc1ccc2SCc3ccccc3C(=O)c2c1
Show InChI InChI=1S/C16H12O3S/c17-15(18)8-10-5-6-14-13(7-10)16(19)12-4-2-1-3-11(12)9-20-14/h1-7H,8-9H2,(H,17,18)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 5.50E+3n/an/an/an/an/an/a



Novartis Institutes for Biomedical Research

Curated by ChEMBL


Assay Description
Inhibition of ATPase activity of Tyr473Ala mutated Helicase4 in presence of ATP (5x Km(ATP)) and dT25 (5x KDNA)


Bioorg Med Chem Lett 16: 923-7 (2006)


Article DOI: 10.1016/j.bmcl.2005.10.110
BindingDB Entry DOI: 10.7270/Q2MS3SB8
More data for this
Ligand-Target Pair