Compile Data Set for Download or QSAR

Found 4 hits of ic50 for monomerid = 50184455   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50184455 (CHEMBL3824323) Show SMILES Cc1nn(C2CCN(CCO)CC2)c(C)c1Nc1ncc(Cl)c(n1)-c1cnn2ccccc12 Show InChI InChI=1S/C23H27ClN8O/c1-15-21(16(2)32(29-15)17-6-9-30(10-7-17)11-12-33)27-23-25-14-19(24)22(28-23)18-13-26-31-8-4-3-5-20(18)31/h3-5,8,13-14,17,33H,6-7,9-12H2,1-2H3,(H,25,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human IGF-1R using fluorescent labeled FL-KKSRGDYMTMQIG-CONH2 as substrate after 1 hr 50 mins				J Med Chem 59: 4859-66 (2016) Article DOI: 10.1021/acs.jmedchem.6b00203 BindingDB Entry DOI: 10.7270/Q2KS6TG9
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50184455 (CHEMBL3824323) Show SMILES Cc1nn(C2CCN(CCO)CC2)c(C)c1Nc1ncc(Cl)c(n1)-c1cnn2ccccc12 Show InChI InChI=1S/C23H27ClN8O/c1-15-21(16(2)32(29-15)17-6-9-30(10-7-17)11-12-33)27-23-25-14-19(24)22(28-23)18-13-26-31-8-4-3-5-20(18)31/h3-5,8,13-14,17,33H,6-7,9-12H2,1-2H3,(H,25,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of IGF1-induced human IGF1R autophosphorylation expressed in IGF-1R knock-out mouse fibroblasts				J Med Chem 59: 4859-66 (2016) Article DOI: 10.1021/acs.jmedchem.6b00203 BindingDB Entry DOI: 10.7270/Q2KS6TG9
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50184455 (CHEMBL3824323) Show SMILES Cc1nn(C2CCN(CCO)CC2)c(C)c1Nc1ncc(Cl)c(n1)-c1cnn2ccccc12 Show InChI InChI=1S/C23H27ClN8O/c1-15-21(16(2)32(29-15)17-6-9-30(10-7-17)11-12-33)27-23-25-14-19(24)22(28-23)18-13-26-31-8-4-3-5-20(18)31/h3-5,8,13-14,17,33H,6-7,9-12H2,1-2H3,(H,25,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human ERG expressed in CHOK1 cells after 6 mins by electrophysiology assay				J Med Chem 59: 4859-66 (2016) Article DOI: 10.1021/acs.jmedchem.6b00203 BindingDB Entry DOI: 10.7270/Q2KS6TG9
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50184455 (CHEMBL3824323) Show SMILES Cc1nn(C2CCN(CCO)CC2)c(C)c1Nc1ncc(Cl)c(n1)-c1cnn2ccccc12 Show InChI InChI=1S/C23H27ClN8O/c1-15-21(16(2)32(29-15)17-6-9-30(10-7-17)11-12-33)27-23-25-14-19(24)22(28-23)18-13-26-31-8-4-3-5-20(18)31/h3-5,8,13-14,17,33H,6-7,9-12H2,1-2H3,(H,25,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of CYP3A4 (unknown origin)				J Med Chem 59: 4859-66 (2016) Article DOI: 10.1021/acs.jmedchem.6b00203 BindingDB Entry DOI: 10.7270/Q2KS6TG9
					More data for this Ligand-Target Pair