Found 5 hits of ic50 for monomerid = 50185170 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50185170
(2-(1H-indazol-3-yl)-5-(4-(piperidin-1-yl)piperidin...)Show SMILES C1CCN(CC1)C1CCN(CC1)c1ccc2nc([nH]c2c1)-c1n[nH]c2ccccc12 Show InChI InChI=1S/C24H28N6/c1-4-12-29(13-5-1)17-10-14-30(15-11-17)18-8-9-21-22(16-18)26-24(25-21)23-19-6-2-3-7-20(19)27-28-23/h2-3,6-9,16-17H,1,4-5,10-15H2,(H,25,26)(H,27,28) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Chiron Corporation
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 |
Bioorg Med Chem Lett 16: 3595-9 (2006)
Article DOI: 10.1016/j.bmcl.2006.03.069
BindingDB Entry DOI: 10.7270/Q2BZ65N7 |
More data for this
Ligand-Target Pair | |
Fibroblast growth factor receptor 1
(Homo sapiens (Human)) | BDBM50185170
(2-(1H-indazol-3-yl)-5-(4-(piperidin-1-yl)piperidin...)Show SMILES C1CCN(CC1)C1CCN(CC1)c1ccc2nc([nH]c2c1)-c1n[nH]c2ccccc12 Show InChI InChI=1S/C24H28N6/c1-4-12-29(13-5-1)17-10-14-30(15-11-17)18-8-9-21-22(16-18)26-24(25-21)23-19-6-2-3-7-20(19)27-28-23/h2-3,6-9,16-17H,1,4-5,10-15H2,(H,25,26)(H,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
Chiron Corporation
Curated by ChEMBL
| Assay Description
Inhibition of FGFR1 |
Bioorg Med Chem Lett 16: 3595-9 (2006)
Article DOI: 10.1016/j.bmcl.2006.03.069
BindingDB Entry DOI: 10.7270/Q2BZ65N7 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Mus musculus) | BDBM50185170
(2-(1H-indazol-3-yl)-5-(4-(piperidin-1-yl)piperidin...)Show SMILES C1CCN(CC1)C1CCN(CC1)c1ccc2nc([nH]c2c1)-c1n[nH]c2ccccc12 Show InChI InChI=1S/C24H28N6/c1-4-12-29(13-5-1)17-10-14-30(15-11-17)18-8-9-21-22(16-18)26-24(25-21)23-19-6-2-3-7-20(19)27-28-23/h2-3,6-9,16-17H,1,4-5,10-15H2,(H,25,26)(H,27,28) | PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 78 | n/a | n/a | n/a | n/a | n/a | n/a |
Chiron Corporation
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 |
Bioorg Med Chem Lett 16: 3595-9 (2006)
Article DOI: 10.1016/j.bmcl.2006.03.069
BindingDB Entry DOI: 10.7270/Q2BZ65N7 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein kinase ABL1
(Homo sapiens (Human)) | BDBM50185170
(2-(1H-indazol-3-yl)-5-(4-(piperidin-1-yl)piperidin...)Show SMILES C1CCN(CC1)C1CCN(CC1)c1ccc2nc([nH]c2c1)-c1n[nH]c2ccccc12 Show InChI InChI=1S/C24H28N6/c1-4-12-29(13-5-1)17-10-14-30(15-11-17)18-8-9-21-22(16-18)26-24(25-21)23-19-6-2-3-7-20(19)27-28-23/h2-3,6-9,16-17H,1,4-5,10-15H2,(H,25,26)(H,27,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Chiron Corporation
Curated by ChEMBL
| Assay Description
Inhibition of c-ABL |
Bioorg Med Chem Lett 16: 3789-92 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.043
BindingDB Entry DOI: 10.7270/Q2HD7WG3 |
More data for this
Ligand-Target Pair | |
Platelet-derived growth factor receptor beta
(Mus musculus (mouse)) | BDBM50185170
(2-(1H-indazol-3-yl)-5-(4-(piperidin-1-yl)piperidin...)Show SMILES C1CCN(CC1)C1CCN(CC1)c1ccc2nc([nH]c2c1)-c1n[nH]c2ccccc12 Show InChI InChI=1S/C24H28N6/c1-4-12-29(13-5-1)17-10-14-30(15-11-17)18-8-9-21-22(16-18)26-24(25-21)23-19-6-2-3-7-20(19)27-28-23/h2-3,6-9,16-17H,1,4-5,10-15H2,(H,25,26)(H,27,28) | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 690 | n/a | n/a | n/a | n/a | n/a | n/a |
Chiron Corporation
Curated by ChEMBL
| Assay Description
Inhibition of PDGFRbeta |
Bioorg Med Chem Lett 16: 3595-9 (2006)
Article DOI: 10.1016/j.bmcl.2006.03.069
BindingDB Entry DOI: 10.7270/Q2BZ65N7 |
More data for this
Ligand-Target Pair | |
Search and Browse
