BindingDB PrimarySearch

Found 10 hits of ic50 for monomerid = 50210461
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Protein arginine N-methyltransferase 1 [11-371] (Homo sapiens (Human))	BDBM50210461 ((stilbamidine)4-[2-[4-amino(imino)methylphenyl]-(E...) Show SMILES NC(=N)c1ccc(\C=C\c2ccc(cc2)C(N)=N)cc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.52E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Georgia Curated by ChEMBL					Assay Description Inhibition of His6x-tagged recombinant PRMT1 (unknown origin) expressed in Escherichia coli BL21(DE3) using [3H]SAM and histone H4 (1 to 20) as subst...				J Med Chem 57: 2611-22 (2014) Article DOI: 10.1021/jm401884z BindingDB Entry DOI: 10.7270/Q2ZW1NFB
The University of Georgia Curated by ChEMBL					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 1 (Homo sapiens)	BDBM50210461 ((stilbamidine)4-[2-[4-amino(imino)methylphenyl]-(E...) Show SMILES NC(=N)c1ccc(\C=C\c2ccc(cc2)C(N)=N)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.52E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PRMT1 (unknown origin)				Citation and Details Article DOI: 10.1039/d0md00259c BindingDB Entry DOI: 10.7270/Q29P3583
TBA					More data for this Ligand-Target Pair
RmtA (Emericella nidulans)	BDBM50210461 ((stilbamidine)4-[2-[4-amino(imino)methylphenyl]-(E...) Show SMILES NC(=N)c1ccc(\C=C\c2ccc(cc2)C(N)=N)cc1 Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.99E+4	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-University of Freiburg Curated by ChEMBL					Assay Description Inhibition of Aspergillus nidulans RmtA by TRF assay				J Med Chem 50: 2319-25 (2007) Article DOI: 10.1021/jm061250e BindingDB Entry DOI: 10.7270/Q2862H8Q
Albert-Ludwigs-University of Freiburg Curated by ChEMBL					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 5 (Homo sapiens (Human))	BDBM50210461 ((stilbamidine)4-[2-[4-amino(imino)methylphenyl]-(E...) Show SMILES NC(=N)c1ccc(\C=C\c2ccc(cc2)C(N)=N)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	4.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Georgia Curated by ChEMBL					Assay Description Inhibition of HA-tagged recombinant PRMT5 (unknown origin) expressed in HEK293T cells using [3H]SAM and histone H4 (1 to 20) as substrate after 8 min...				J Med Chem 57: 2611-22 (2014) Article DOI: 10.1021/jm401884z BindingDB Entry DOI: 10.7270/Q2ZW1NFB
The University of Georgia Curated by ChEMBL					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 1 [11-371] (Homo sapiens (Human))	BDBM50210461 ((stilbamidine)4-[2-[4-amino(imino)methylphenyl]-(E...) Show SMILES NC(=N)c1ccc(\C=C\c2ccc(cc2)C(N)=N)cc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	5.66E+4	n/a	n/a	n/a	n/a	n/a	n/a
Georgia State University Curated by ChEMBL					Assay Description Inhibition of human GST-tagged PRMT1-mediated arginine methylation expressed in Escherichia coli BL21 (DE3) using H4(1-20) and [14C]-AdoMet by scinti...				J Med Chem 53: 6028-39 (2010) Article DOI: 10.1021/jm100416n BindingDB Entry DOI: 10.7270/Q2251JDB
Georgia State University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 1 [11-371] (Homo sapiens (Human))	BDBM50210461 ((stilbamidine)4-[2-[4-amino(imino)methylphenyl]-(E...) Show SMILES NC(=N)c1ccc(\C=C\c2ccc(cc2)C(N)=N)cc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	5.69E+4	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-University of Freiburg Curated by ChEMBL					Assay Description Inhibition of human recombinant PRMT1 by TRF assay				J Med Chem 50: 2319-25 (2007) Article DOI: 10.1021/jm061250e BindingDB Entry DOI: 10.7270/Q2862H8Q
Albert-Ludwigs-University of Freiburg Curated by ChEMBL					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 1 [11-371] (Homo sapiens (Human))	BDBM50210461 ((stilbamidine)4-[2-[4-amino(imino)methylphenyl]-(E...) Show SMILES NC(=N)c1ccc(\C=C\c2ccc(cc2)C(N)=N)cc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.06E+5	n/a	n/a	n/a	n/a	n/a	n/a
Georgia State University Curated by ChEMBL					Assay Description Inhibition of His6x-tagged PRMT1-mediated protein arginine methylation expressed in Escherichia coli BL21 (DE3) using H4(1-20) and [14C]-SAM by scint...				J Med Chem 53: 6028-39 (2010) Article DOI: 10.1021/jm100416n BindingDB Entry DOI: 10.7270/Q2251JDB
Georgia State University Curated by ChEMBL					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 6 (Homo sapiens (Human))	BDBM50210461 ((stilbamidine)4-[2-[4-amino(imino)methylphenyl]-(E...) Show SMILES NC(=N)c1ccc(\C=C\c2ccc(cc2)C(N)=N)cc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.73E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Georgia Curated by ChEMBL					Assay Description Inhibition of His6x-tagged PRMT6 (unknown origin) using [3H]SAM and histone H3.1 as substrate at 20 uM after 1 hr by P81 filter binding assay				J Med Chem 57: 2611-22 (2014) Article DOI: 10.1021/jm401884z BindingDB Entry DOI: 10.7270/Q2ZW1NFB
The University of Georgia Curated by ChEMBL					More data for this Ligand-Target Pair
Histone-arginine methyltransferase CARM1 (Homo sapiens (Human))	BDBM50210461 ((stilbamidine)4-[2-[4-amino(imino)methylphenyl]-(E...) Show SMILES NC(=N)c1ccc(\C=C\c2ccc(cc2)C(N)=N)cc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Georgia Curated by ChEMBL					Assay Description Inhibition of GST-tagged CARM1 (unknown origin) using [3H]SAM and histone H3.1 as substrate at 20 uM after 1 hr by P81 filter binding assay				J Med Chem 57: 2611-22 (2014) Article DOI: 10.1021/jm401884z BindingDB Entry DOI: 10.7270/Q2ZW1NFB
The University of Georgia Curated by ChEMBL					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 1 [11-371] (Homo sapiens (Human))	BDBM50210461 ((stilbamidine)4-[2-[4-amino(imino)methylphenyl]-(E...) Show SMILES NC(=N)c1ccc(\C=C\c2ccc(cc2)C(N)=N)cc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.15E+6	n/a	n/a	n/a	n/a	n/a	n/a
Georgia State University Curated by ChEMBL					Assay Description Inhibition of His6x-tagged PRMT1-mediated protein arginine methylation expressed in Escherichia coli BL21 (DE3) using GAR R4 peptide and [14C]-AdoMet...				J Med Chem 53: 6028-39 (2010) Article DOI: 10.1021/jm100416n BindingDB Entry DOI: 10.7270/Q2251JDB
Georgia State University Curated by ChEMBL					More data for this Ligand-Target Pair