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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50235466   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Farnesyl pyrophosphate synthase


(Homo sapiens (Human))		BDBM50235466
PNG
(CHEMBL4097575)
Show SMILES Cc1c(sc2ncnc(NCP(O)(O)=O)c12)-c1ccc(C)cc1
Show InChI InChI=1S/C15H16N3O3PS/c1-9-3-5-11(6-4-9)13-10(2)12-14(18-8-22(19,20)21)16-7-17-15(12)23-13/h3-7H,8H2,1-2H3,(H,16,17,18)(H2,19,20,21)
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Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



McGill University

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His-tagged human recombinant FPPS expressed in Escherichia coli BL21 (DE3) using GPP and [3H]-IPP as substrate preincubated ...

J Med Chem 60: 2119-2134 (2017)


Article DOI: 10.1021/acs.jmedchem.6b01888
BindingDB Entry DOI: 10.7270/Q23F4RXR
More data for this
Ligand-Target Pair