Found 5 hits of ic50 for monomerid = 50237207 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50237207
((2S)-3-(3-(2-chloro-4-(methylsulfonyl)phenyl)-1,2,...)Show SMILES [#6]-[#6](-[#6@H](-[#7])-[#6](\F)=[#6]-1/[#6]-[#6]-[#6]-[#6]-1)-c1nc(no1)-c1ccc(cc1Cl)S([#6])(=O)=O |r| Show InChI InChI=1S/C18H21ClFN3O3S/c1-10(16(21)15(20)11-5-3-4-6-11)18-22-17(23-26-18)13-8-7-12(9-14(13)19)27(2,24)25/h7-10,16H,3-6,21H2,1-2H3/t10?,16-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co. Inc.
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DPP4 expressed in insect cell |
Bioorg Med Chem Lett 18: 2409-13 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.050 BindingDB Entry DOI: 10.7270/Q2HD7WJ0 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 2
(Homo sapiens (Human)) | BDBM50237207
((2S)-3-(3-(2-chloro-4-(methylsulfonyl)phenyl)-1,2,...)Show SMILES [#6]-[#6](-[#6@H](-[#7])-[#6](\F)=[#6]-1/[#6]-[#6]-[#6]-[#6]-1)-c1nc(no1)-c1ccc(cc1Cl)S([#6])(=O)=O |r| Show InChI InChI=1S/C18H21ClFN3O3S/c1-10(16(21)15(20)11-5-3-4-6-11)18-22-17(23-26-18)13-8-7-12(9-14(13)19)27(2,24)25/h7-10,16H,3-6,21H2,1-2H3/t10?,16-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
Matrix Laboratories Limited
Curated by ChEMBL
| Assay Description Inhibition of QPP |
Bioorg Med Chem 17: 1783-802 (2009)
Article DOI: 10.1016/j.bmc.2009.01.061 BindingDB Entry DOI: 10.7270/Q2VD70DJ |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 2
(Homo sapiens (Human)) | BDBM50237207
((2S)-3-(3-(2-chloro-4-(methylsulfonyl)phenyl)-1,2,...)Show SMILES [#6]-[#6](-[#6@H](-[#7])-[#6](\F)=[#6]-1/[#6]-[#6]-[#6]-[#6]-1)-c1nc(no1)-c1ccc(cc1Cl)S([#6])(=O)=O |r| Show InChI InChI=1S/C18H21ClFN3O3S/c1-10(16(21)15(20)11-5-3-4-6-11)18-22-17(23-26-18)13-8-7-12(9-14(13)19)27(2,24)25/h7-10,16H,3-6,21H2,1-2H3/t10?,16-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co. Inc.
Curated by ChEMBL
| Assay Description Inhibition of human recombinant QPP expressed in baculovirus system |
Bioorg Med Chem Lett 18: 2409-13 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.050 BindingDB Entry DOI: 10.7270/Q2HD7WJ0 |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50237207
((2S)-3-(3-(2-chloro-4-(methylsulfonyl)phenyl)-1,2,...)Show SMILES [#6]-[#6](-[#6@H](-[#7])-[#6](\F)=[#6]-1/[#6]-[#6]-[#6]-[#6]-1)-c1nc(no1)-c1ccc(cc1Cl)S([#6])(=O)=O |r| Show InChI InChI=1S/C18H21ClFN3O3S/c1-10(16(21)15(20)11-5-3-4-6-11)18-22-17(23-26-18)13-8-7-12(9-14(13)19)27(2,24)25/h7-10,16H,3-6,21H2,1-2H3/t10?,16-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Matrix Laboratories Limited
Curated by ChEMBL
| Assay Description Inhibition of human ERG |
Bioorg Med Chem 17: 1783-802 (2009)
Article DOI: 10.1016/j.bmc.2009.01.061 BindingDB Entry DOI: 10.7270/Q2VD70DJ |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50237207
((2S)-3-(3-(2-chloro-4-(methylsulfonyl)phenyl)-1,2,...)Show SMILES [#6]-[#6](-[#6@H](-[#7])-[#6](\F)=[#6]-1/[#6]-[#6]-[#6]-[#6]-1)-c1nc(no1)-c1ccc(cc1Cl)S([#6])(=O)=O |r| Show InChI InChI=1S/C18H21ClFN3O3S/c1-10(16(21)15(20)11-5-3-4-6-11)18-22-17(23-26-18)13-8-7-12(9-14(13)19)27(2,24)25/h7-10,16H,3-6,21H2,1-2H3/t10?,16-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co. Inc.
Curated by ChEMBL
| Assay Description Inhibition of human ERG |
Bioorg Med Chem Lett 18: 2409-13 (2008)
Article DOI: 10.1016/j.bmcl.2008.02.050 BindingDB Entry DOI: 10.7270/Q2HD7WJ0 |
More data for this Ligand-Target Pair | |