Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Integrase (Human immunodeficiency virus 1) | BDBM50237838 ((R)-3-(4,5-dihydroxy-2-nitrophenyl)-2-(3-(4,5-dihy...) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Lille 1 Curated by ChEMBL | Assay Description Inhibition of HIV1 integrase using labelled U5A/U5B double stranded DNA substrate | J Med Chem 51: 2575-9 (2008) Article DOI: 10.1021/jm7011134 BindingDB Entry DOI: 10.7270/Q26M39K5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50237838 ((R)-3-(4,5-dihydroxy-2-nitrophenyl)-2-(3-(4,5-dihy...) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Lille 1 Curated by ChEMBL | Assay Description Inhibition of HIV1 integrase strand transfer activity using labelled oligonucleotide substrate by ELISA | J Med Chem 51: 2575-9 (2008) Article DOI: 10.1021/jm7011134 BindingDB Entry DOI: 10.7270/Q26M39K5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50237838 ((R)-3-(4,5-dihydroxy-2-nitrophenyl)-2-(3-(4,5-dihy...) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Lille 1 Curated by ChEMBL | Assay Description Inhibition of HIV1 integrase using labelled oligonucleotide substrate by ELISA | J Med Chem 51: 2575-9 (2008) Article DOI: 10.1021/jm7011134 BindingDB Entry DOI: 10.7270/Q26M39K5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human)) | BDBM50237838 ((R)-3-(4,5-dihydroxy-2-nitrophenyl)-2-(3-(4,5-dihy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 741 | n/a | n/a | n/a | n/a | n/a | n/a |
National Hellenic Research Foundation Curated by ChEMBL | Assay Description Inhibition of aldose reductase | Eur J Med Chem 45: 1663-6 (2010) Article DOI: 10.1016/j.ejmech.2009.12.007 BindingDB Entry DOI: 10.7270/Q2N58MJW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50237838 ((R)-3-(4,5-dihydroxy-2-nitrophenyl)-2-(3-(4,5-dihy...) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.08E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Lille 1 Curated by ChEMBL | Assay Description Inhibition of HIV1 integrase using labelled oligonucleotide substrate in presence of bovine serum albumin by ELISA | J Med Chem 51: 2575-9 (2008) Article DOI: 10.1021/jm7011134 BindingDB Entry DOI: 10.7270/Q26M39K5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50237838 ((R)-3-(4,5-dihydroxy-2-nitrophenyl)-2-(3-(4,5-dihy...) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.22E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Lille 1 Curated by ChEMBL | Assay Description Inhibition of HIV1 integrase 3'-processing activity using labelled oligonucleotide substrate by ELISA | J Med Chem 51: 2575-9 (2008) Article DOI: 10.1021/jm7011134 BindingDB Entry DOI: 10.7270/Q26M39K5 | |||||||||||
More data for this Ligand-Target Pair |