Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Diacylglycerol lipase-alpha (Homo sapiens (Human)) | BDBM50274020 (CHEMBL514886 | N-Formyl-beta-alanine-(1S)-1-[[(2S,...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Università di Roma Curated by ChEMBL | Assay Description Inhibition of human recombinant DAGLalpha-mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in african green monkey ... | J Med Chem 51: 6970-9 (2008) Article DOI: 10.1021/jm800978m BindingDB Entry DOI: 10.7270/Q2251J1D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat)) | BDBM50274020 (CHEMBL514886 | N-Formyl-beta-alanine-(1S)-1-[[(2S,...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sapienza Università di Roma Curated by ChEMBL | Assay Description Inhibition of FAAH-mediated [14C]anadamide hydrolysis in rat brain membrane | J Med Chem 51: 6970-9 (2008) Article DOI: 10.1021/jm800978m BindingDB Entry DOI: 10.7270/Q2251J1D | |||||||||||
More data for this Ligand-Target Pair |