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Compile Data Set for Download or QSAR

Found 4 hits of ic50 for monomerid = 50304112   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50304112
PNG
((Z)-5'-Amino-1H,1'H-[2,3']biindolylidene-3,2'-dion...)
Show SMILES Nc1ccc2NC(=O)C(c2c1)c1[nH]c2ccccc2c1N=O
Show InChI InChI=1S/C16H12N4O2/c17-8-5-6-12-10(7-8)13(16(21)19-12)15-14(20-22)9-3-1-2-4-11(9)18-15/h1-7,13,18H,17H2,(H,19,21)
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Article
PubMed
n/an/a 128n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of FLT3 by HTRF assay


Bioorg Med Chem Lett 20: 2033-7 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.039
BindingDB Entry DOI: 10.7270/Q29W0GF0
More data for this
Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1


(Homo sapiens (Human))
BDBM50304112
PNG
((Z)-5'-Amino-1H,1'H-[2,3']biindolylidene-3,2'-dion...)
Show SMILES Nc1ccc2NC(=O)C(c2c1)c1[nH]c2ccccc2c1N=O
Show InChI InChI=1S/C16H12N4O2/c17-8-5-6-12-10(7-8)13(16(21)19-12)15-14(20-22)9-3-1-2-4-11(9)18-15/h1-7,13,18H,17H2,(H,19,21)
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Article
PubMed
n/an/a 150n/an/an/an/an/an/a



Universit£ de La Rochelle

Curated by ChEMBL


Assay Description
Inhibition of GST-fused CDK5/p25 expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation counting


Bioorg Med Chem 17: 6257-63 (2009)


Article DOI: 10.1016/j.bmc.2009.07.051
BindingDB Entry DOI: 10.7270/Q2BR8S9W
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase 17B


(Homo sapiens (Human))
BDBM50304112
PNG
((Z)-5'-Amino-1H,1'H-[2,3']biindolylidene-3,2'-dion...)
Show SMILES Nc1ccc2NC(=O)C(c2c1)c1[nH]c2ccccc2c1N=O
Show InChI InChI=1S/C16H12N4O2/c17-8-5-6-12-10(7-8)13(16(21)19-12)15-14(20-22)9-3-1-2-4-11(9)18-15/h1-7,13,18H,17H2,(H,19,21)
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Article
PubMed
n/an/a 250n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Inhibition of DRAK2 (unknown origin) using MRLC3 peptide as substrate incubated for 2 hrs by ADP-Glo kinase assay


Bioorg Med Chem Lett 26: 2719-23 (2016)


Article DOI: 10.1016/j.bmcl.2016.03.111
BindingDB Entry DOI: 10.7270/Q2N29ZTZ
More data for this
Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A


(RAT)
BDBM50304112
PNG
((Z)-5'-Amino-1H,1'H-[2,3']biindolylidene-3,2'-dion...)
Show SMILES Nc1ccc2NC(=O)C(c2c1)c1[nH]c2ccccc2c1N=O
Show InChI InChI=1S/C16H12N4O2/c17-8-5-6-12-10(7-8)13(16(21)19-12)15-14(20-22)9-3-1-2-4-11(9)18-15/h1-7,13,18H,17H2,(H,19,21)
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PC sid
UniChem

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Article
PubMed
n/an/a 4.20E+3n/an/an/an/an/an/a



Universit£ de La Rochelle

Curated by ChEMBL


Assay Description
Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli assessed as [gamma-33P]ATP incorporation after 10 mins by scintillation ...


Bioorg Med Chem 17: 6257-63 (2009)


Article DOI: 10.1016/j.bmc.2009.07.051
BindingDB Entry DOI: 10.7270/Q2BR8S9W
More data for this
Ligand-Target Pair