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Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 50323812   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone-lysine N-methyltransferase EHMT2


(Homo sapiens (Human))		BDBM50323812
PNG
(7-(5-Aminopentyloxy)-6-methoxy-2-(4-methyl-1,4-dia...)
Show SMILES COc1cc2c(NC3CCN(C)CC3)nc(nc2cc1OCCCCCN)N1CCCN(C)CC1
Show InChI InChI=1S/C26H43N7O2/c1-31-11-7-12-33(16-15-31)26-29-22-19-24(35-17-6-4-5-10-27)23(34-3)18-21(22)25(30-26)28-20-8-13-32(2)14-9-20/h18-20H,4-17,27H2,1-3H3,(H,28,29,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.10E+5n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assay

J Med Chem 53: 5844-57 (2010)


Article DOI: 10.1021/jm100478y
BindingDB Entry DOI: 10.7270/Q2DZ08H1
More data for this
Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT2


(Homo sapiens (Human))		BDBM50323812
PNG
(7-(5-Aminopentyloxy)-6-methoxy-2-(4-methyl-1,4-dia...)
Show SMILES COc1cc2c(NC3CCN(C)CC3)nc(nc2cc1OCCCCCN)N1CCCN(C)CC1
Show InChI InChI=1S/C26H43N7O2/c1-31-11-7-12-33(16-15-31)26-29-22-19-24(35-17-6-4-5-10-27)23(34-3)18-21(22)25(30-26)28-20-8-13-32(2)14-9-20/h18-20H,4-17,27H2,1-3H3,(H,28,29,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.35E+5n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assay

J Med Chem 53: 5844-57 (2010)


Article DOI: 10.1021/jm100478y
BindingDB Entry DOI: 10.7270/Q2DZ08H1
More data for this
Ligand-Target Pair