Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM50333952 (CHEMBL1644470 | exo-(1R,5S)-3-(6-phenylpyridin-2-y...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
MSD Curated by ChEMBL | Assay Description Inhibition of [3H]noradrenalin reuptake at NET expressed in MDCK cells scintillation counting | Bioorg Med Chem Lett 21: 271-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.021 BindingDB Entry DOI: 10.7270/Q2CZ37D3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50333952 (CHEMBL1644470 | exo-(1R,5S)-3-(6-phenylpyridin-2-y...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7.64E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
MSD Curated by ChEMBL | Assay Description Inhibition of [3H]serotonin reuptake at SERT expressed in HEK293 cells scintillation counting | Bioorg Med Chem Lett 21: 271-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.021 BindingDB Entry DOI: 10.7270/Q2CZ37D3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM50333952 (CHEMBL1644470 | exo-(1R,5S)-3-(6-phenylpyridin-2-y...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
MSD Curated by ChEMBL | Assay Description Inhibition of [3H]dopamine reuptake at DAT expressed in HEK293 cells scintillation counting | Bioorg Med Chem Lett 21: 271-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.021 BindingDB Entry DOI: 10.7270/Q2CZ37D3 | |||||||||||
More data for this Ligand-Target Pair |