Compile Data Set for Download or QSAR

Found 4 hits of ic50 for monomerid = 50337145   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 7 (Homo sapiens (Human))	BDBM50337145 (9-chloro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)p...) Show SMILES COc1cc(ccc1Nc1ncc2N(C)C(=O)c3ccc(Cl)cc3N(C)c2n1)N1CCN(C)CC1 Show InChI InChI=1S/C25H28ClN7O2/c1-30-9-11-33(12-10-30)17-6-8-19(22(14-17)35-4)28-25-27-15-21-23(29-25)31(2)20-13-16(26)5-7-18(20)24(34)32(21)3/h5-8,13-15H,9-12H2,1-4H3,(H,27,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of ERK5 in human HeLa cells assessed as reduction in EGF-induced ERK5 autophosphorylation pretreated for 1 hr followed by EGF stimulation ...				J Med Chem 63: 7817-7826 (2020) Article DOI: 10.1021/acs.jmedchem.0c00596 BindingDB Entry DOI: 10.7270/Q2SB4981
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase DCLK1 (Homo sapiens (Human))	BDBM50337145 (9-chloro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)p...) Show SMILES COc1cc(ccc1Nc1ncc2N(C)C(=O)c3ccc(Cl)cc3N(C)c2n1)N1CCN(C)CC1 Show InChI InChI=1S/C25H28ClN7O2/c1-30-9-11-33(12-10-30)17-6-8-19(22(14-17)35-4)28-25-27-15-21-23(29-25)31(2)20-13-16(26)5-7-18(20)24(34)32(21)3/h5-8,13-15H,9-12H2,1-4H3,(H,27,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-tagged DCLK1 (G351 to H689 residues) expressed in Escherichia coli BL21 DE3 using 5-FAM-KKLRRTLSVA-CO...				J Med Chem 63: 7817-7826 (2020) Article DOI: 10.1021/acs.jmedchem.0c00596 BindingDB Entry DOI: 10.7270/Q2SB4981
					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50337145 (9-chloro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)p...) Show SMILES COc1cc(ccc1Nc1ncc2N(C)C(=O)c3ccc(Cl)cc3N(C)c2n1)N1CCN(C)CC1 Show InChI InChI=1S/C25H28ClN7O2/c1-30-9-11-33(12-10-30)17-6-8-19(22(14-17)35-4)28-25-27-15-21-23(29-25)31(2)20-13-16(26)5-7-18(20)24(34)32(21)3/h5-8,13-15H,9-12H2,1-4H3,(H,27,28,29)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of recombinant human GST-tagged LRRK2 catalytic domain (970 to 2527 residues) expressed in baculovirus expression system using LRRKtide as...				J Med Chem 63: 7817-7826 (2020) Article DOI: 10.1021/acs.jmedchem.0c00596 BindingDB Entry DOI: 10.7270/Q2SB4981
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 7 (Homo sapiens (Human))	BDBM50337145 (9-chloro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)p...) Show SMILES COc1cc(ccc1Nc1ncc2N(C)C(=O)c3ccc(Cl)cc3N(C)c2n1)N1CCN(C)CC1 Show InChI InChI=1S/C25H28ClN7O2/c1-30-9-11-33(12-10-30)17-6-8-19(22(14-17)35-4)28-25-27-15-21-23(29-25)31(2)20-13-16(26)5-7-18(20)24(34)32(21)3/h5-8,13-15H,9-12H2,1-4H3,(H,27,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.14E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of EGF-induced BMK1 autophosphorylation in human HeLa cells by SDS-PAGE analysis				ACS Med Chem Lett 2: 195-200 (2011) Article DOI: 10.1021/ml100304b BindingDB Entry DOI: 10.7270/Q2222VSB
					More data for this Ligand-Target Pair