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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50342747   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Isoprenylcysteine carboxyl methyltransferase


(Homo sapiens (Human))
BDBM50342747
PNG
(3-nitrophenyl-sulfonamido-farnesylcysteine | CHEMB...)
Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#16]-[#6]-[#6@H](-[#7]S(=O)(=O)c1cccc(c1)-[#7+](-[#8-])=O)-[#6](-[#8])=O |r|
Show InChI InChI=1S/C24H34N2O6S2/c1-18(2)8-5-9-19(3)10-6-11-20(4)14-15-33-17-23(24(27)28)25-34(31,32)22-13-7-12-21(16-22)26(29)30/h7-8,10,12-14,16,23,25H,5-6,9,11,15,17H2,1-4H3,(H,27,28)/b19-10+,20-14+/t23-/m0/s1
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.34E+4n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of human ICMT incubated with N-Acetyl-S-farnesyl-L-cysteine substrate for 5 mins followed by addition of [14C]-SAM measured after 30 mins ...


Bioorg Med Chem Lett 21: 2616-20 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.078
BindingDB Entry DOI: 10.7270/Q2348KNH
More data for this
Ligand-Target Pair