Home
Info
Download
About us
Email us
Contribute data
Web Services
Beta Site
myBDB
logout
Search and Browse
Target
Sequence
Name
&
Ki
IC50
Kd
EC50
Rate constants
ΔG°
ΔH°
-TΔS°
pH (Enzymatic Assay)
pH (ITC)
Substrate or Competitor
Compound Mol. Wt.
Chemical Structure
Pathways
Source Organism
Number of Compounds
Monomer List in csv
Het List in SDF
Compound
FDA Drugs
Important Compounds
Chemical Structure
Name
SMILES
Number of Data
/
Targets
Special tools
3D Structure Series
Find My Compound's Targets
Find Compounds for My Targets
Do Virtual Screening
SCOP
Citation
Author
Journal/Citation
Institution
PubMed
PubChem BioAssay
US Patent
Special Data Sets
D3R
Host Guest Systems
Prot-Lig Validation Sets
Other Databases
PDB
85%
100%
Seq ID
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
PubMed
Download
All Compounds & Data
Target Names &
Ki
IC50
Kd
EC50
ΔG°
ΔH°
-TΔS°
Enter Data
Deposition
Contribute data
Sent Comments
Compile Data Set for Download or QSAR
Found
5
hits of ic50 for monomerid = 50401471
Target/Host
(Institution)
Ligand
Target/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
k
off
s
-1
k
on
M
-1
s
-1
pH
Temp
°C
DNA-dependent protein kinase catalytic subunit
(Homo sapiens (Human))
BDBM50401471
(CHEMBL243810)
Show SMILES
O=c1nc(oc2c(cccc12)-c1ccccc1)N1CCOCC1
Show InChI
InChI=1S/C18H16N2O3/c21-17-15-8-4-7-14(13-5-2-1-3-6-13)16(15)23-18(19-17)20-9-11-22-12-10-20/h1-8H,9-12H2
PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
CHEMBL
PC cid
PC sid
UniChem
Similars
Article
PubMed
n/a
n/a
300
n/a
n/a
n/a
n/a
n/a
n/a
La Trobe University
Curated by
ChEMBL
Assay Description
Inhibition of DNA-PK using EPPLSQEAFADLWKK as substrate after 5 mins by ADP-Glo kinase assay
Eur J Med Chem
57:
85
-
101
(2012)
Article DOI:
10.1016/j.ejmech.2012.08.035
BindingDB Entry DOI:
10.7270/Q2XS5WK6
More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human))
BDBM50401471
(CHEMBL243810)
Show SMILES
O=c1nc(oc2c(cccc12)-c1ccccc1)N1CCOCC1
Show InChI
InChI=1S/C18H16N2O3/c21-17-15-8-4-7-14(13-5-2-1-3-6-13)16(15)23-18(19-17)20-9-11-22-12-10-20/h1-8H,9-12H2
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
CHEMBL
PC cid
PC sid
UniChem
Similars
Article
PubMed
n/a
n/a
950
n/a
n/a
n/a
n/a
n/a
n/a
La Trobe University
Curated by
ChEMBL
Assay Description
Inhibition of PI3Kdelta by HTRF assay in presence of ATP
Eur J Med Chem
57:
85
-
101
(2012)
Article DOI:
10.1016/j.ejmech.2012.08.035
BindingDB Entry DOI:
10.7270/Q2XS5WK6
More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human))
BDBM50401471
(CHEMBL243810)
Show SMILES
O=c1nc(oc2c(cccc12)-c1ccccc1)N1CCOCC1
Show InChI
InChI=1S/C18H16N2O3/c21-17-15-8-4-7-14(13-5-2-1-3-6-13)16(15)23-18(19-17)20-9-11-22-12-10-20/h1-8H,9-12H2
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
CHEMBL
PC cid
PC sid
UniChem
Similars
Article
PubMed
n/a
n/a
1.50E+3
n/a
n/a
n/a
n/a
n/a
n/a
La Trobe University
Curated by
ChEMBL
Assay Description
Inhibition of PI3Kgamma by HTRF assay in presence of ATP
Eur J Med Chem
57:
85
-
101
(2012)
Article DOI:
10.1016/j.ejmech.2012.08.035
BindingDB Entry DOI:
10.7270/Q2XS5WK6
More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
(Homo sapiens (Human))
BDBM50401471
(CHEMBL243810)
Show SMILES
O=c1nc(oc2c(cccc12)-c1ccccc1)N1CCOCC1
Show InChI
InChI=1S/C18H16N2O3/c21-17-15-8-4-7-14(13-5-2-1-3-6-13)16(15)23-18(19-17)20-9-11-22-12-10-20/h1-8H,9-12H2
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
CHEMBL
PC cid
PC sid
UniChem
Similars
Article
PubMed
n/a
n/a
3.36E+3
n/a
n/a
n/a
n/a
n/a
n/a
La Trobe University
Curated by
ChEMBL
Assay Description
Inhibition of PI3Kbeta by HTRF assay in presence of ATP
Eur J Med Chem
57:
85
-
101
(2012)
Article DOI:
10.1016/j.ejmech.2012.08.035
BindingDB Entry DOI:
10.7270/Q2XS5WK6
More data for this
Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human))
BDBM50401471
(CHEMBL243810)
Show SMILES
O=c1nc(oc2c(cccc12)-c1ccccc1)N1CCOCC1
Show InChI
InChI=1S/C18H16N2O3/c21-17-15-8-4-7-14(13-5-2-1-3-6-13)16(15)23-18(19-17)20-9-11-22-12-10-20/h1-8H,9-12H2
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
CHEMBL
PC cid
PC sid
UniChem
Similars
Article
PubMed
n/a
n/a
4.07E+3
n/a
n/a
n/a
n/a
n/a
n/a
La Trobe University
Curated by
ChEMBL
Assay Description
Inhibition of PI3Kalpha by HTRF assay in presence of ATP
Eur J Med Chem
57:
85
-
101
(2012)
Article DOI:
10.1016/j.ejmech.2012.08.035
BindingDB Entry DOI:
10.7270/Q2XS5WK6
More data for this
Ligand-Target Pair