Compile Data Set for Download or QSAR

Found 4 hits of ic50 for monomerid = 50525007   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50525007 (CHEMBL4440664 | US11401286, Example 6) Show SMILES OCCc1ccc(Nc2cc(nc3CCCc23)-c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C22H21ClN2O/c23-17-4-1-3-16(13-17)21-14-22(19-5-2-6-20(19)25-21)24-18-9-7-15(8-10-18)11-12-26/h1,3-4,7-10,13-14,26H,2,5-6,11-12H2,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	562	n/a	n/a	n/a	n/a	n/a	n/a
Tetra Discovery Partners, Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...				J Med Chem 62: 4884-4901 (2019) Article DOI: 10.1021/acs.jmedchem.9b00193 BindingDB Entry DOI: 10.7270/Q26H4MVT
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D7 [S54D] (Homo sapiens (Human))	BDBM50525007 (CHEMBL4440664 | US11401286, Example 6) Show SMILES OCCc1ccc(Nc2cc(nc3CCCc23)-c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C22H21ClN2O/c23-17-4-1-3-16(13-17)21-14-22(19-5-2-6-20(19)25-21)24-18-9-7-15(8-10-18)11-12-26/h1,3-4,7-10,13-14,26H,2,5-6,11-12H2,(H,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assays are performed in 96-well plates in a total volume of 200 μl/well. Compounds are dissolved in dimethylsulfoxide (DMSO) and added to plates...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MXV
					More data for this Ligand-Target Pair
Isoform 7 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50525007 (CHEMBL4440664 | US11401286, Example 6) Show SMILES OCCc1ccc(Nc2cc(nc3CCCc23)-c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C22H21ClN2O/c23-17-4-1-3-16(13-17)21-14-22(19-5-2-6-20(19)25-21)24-18-9-7-15(8-10-18)11-12-26/h1,3-4,7-10,13-14,26H,2,5-6,11-12H2,(H,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assays are performed in 96-well plates in a total volume of 200 μl/well. Compounds are dissolved in dimethylsulfoxide (DMSO) and added to plates...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MXV
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B [S133D] (Homo sapiens (Human))	BDBM50525007 (CHEMBL4440664 | US11401286, Example 6) Show SMILES OCCc1ccc(Nc2cc(nc3CCCc23)-c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C22H21ClN2O/c23-17-4-1-3-16(13-17)21-14-22(19-5-2-6-20(19)25-21)24-18-9-7-15(8-10-18)11-12-26/h1,3-4,7-10,13-14,26H,2,5-6,11-12H2,(H,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assays are performed in 96-well plates in a total volume of 200 μl/well. Compounds are dissolved in dimethylsulfoxide (DMSO) and added to plates...				Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MXV
					More data for this Ligand-Target Pair