Compile Data Set for Download or QSAR

Found 4 hits of ic50 for monomerid = 50535101   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase B (Homo sapiens (Human))	BDBM50535101 (CHEMBL4444533) Show SMILES CN(C)c1ccc(cn1)-c1cc2nccnc2c(NCC(F)(F)F)n1 Show InChI InChI=1S/C16H15F3N6/c1-25(2)13-4-3-10(8-22-13)11-7-12-14(21-6-5-20-12)15(24-11)23-9-16(17,18)19/h3-8H,9H2,1-2H3,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of N-terminal-6His-tagged full length human Aurora B expressed in baculovirus using 5FAM-PKA-tide as substrate after 120 mins by fluoresce...				Bioorg Med Chem Lett 26: 4606-4612 (2016) Article DOI: 10.1016/j.bmcl.2016.08.070 BindingDB Entry DOI: 10.7270/Q2GM8BT3
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50535101 (CHEMBL4444533) Show SMILES CN(C)c1ccc(cn1)-c1cc2nccnc2c(NCC(F)(F)F)n1 Show InChI InChI=1S/C16H15F3N6/c1-25(2)13-4-3-10(8-22-13)11-7-12-14(21-6-5-20-12)15(24-11)23-9-16(17,18)19/h3-8H,9H2,1-2H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...				Bioorg Med Chem Lett 26: 4606-4612 (2016) Article DOI: 10.1016/j.bmcl.2016.08.070 BindingDB Entry DOI: 10.7270/Q2GM8BT3
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50535101 (CHEMBL4444533) Show SMILES CN(C)c1ccc(cn1)-c1cc2nccnc2c(NCC(F)(F)F)n1 Show InChI InChI=1S/C16H15F3N6/c1-25(2)13-4-3-10(8-22-13)11-7-12-14(21-6-5-20-12)15(24-11)23-9-16(17,18)19/h3-8H,9H2,1-2H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of SYK in human B cells assessed as suppression of anti-IgM-induced CD69 surface expression preincubated for 30 mins followed by anti-IgM ...				Bioorg Med Chem Lett 26: 4606-4612 (2016) Article DOI: 10.1016/j.bmcl.2016.08.070 BindingDB Entry DOI: 10.7270/Q2GM8BT3
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50535101 (CHEMBL4444533) Show SMILES CN(C)c1ccc(cn1)-c1cc2nccnc2c(NCC(F)(F)F)n1 Show InChI InChI=1S/C16H15F3N6/c1-25(2)13-4-3-10(8-22-13)11-7-12-14(21-6-5-20-12)15(24-11)23-9-16(17,18)19/h3-8H,9H2,1-2H3,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<5.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of human ERG expressed in CHOK1 cell membranes after 2 hrs by cy3b-dofetilide-based fluorescence polarization assay				Bioorg Med Chem Lett 26: 4606-4612 (2016) Article DOI: 10.1016/j.bmcl.2016.08.070 BindingDB Entry DOI: 10.7270/Q2GM8BT3
					More data for this Ligand-Target Pair